| Identification | Back Directory | [Name]
4-AMINO-1-ISOPROPYL-1H-PYRAZOLE | [CAS]
97421-16-4 | [Synonyms]
1-ISOPROPYLPYRAZOL-4-AMINE
1-PROPAN-2-YLPYRAZOL-4-AMINE
4-Amino-1-(iso-propyl)pyrazole
1-isopropyl-1H-pyrazol-4-amine
4-AMINO-1-ISOPROPYL-1H-PYRAZOLE
1-isopropyl-1H-pyrazol-4-amine 1HCl
4-AMINO-1-ISOPROPYL-1H-PYRAZOLE HCL
1-(1-methylethyl)-1H-pyrazol-4-amine
1H-Pyrazol-4-amine, 1-(1-methylethyl)-
1-isopropyl-1H-pyrazol-4-amine(SALTDATA: HCl) | [Molecular Formula]
C6H11N3 | [MDL Number]
MFCD08700622 | [MOL File]
97421-16-4.mol | [Molecular Weight]
125.17 |
| Chemical Properties | Back Directory | [Boiling point ]
234.2±13.0 °C(Predicted) | [density ]
1.12±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [pka]
3.74±0.10(Predicted) | [Appearance]
Brown to reddish brown Liquid |
| Hazard Information | Back Directory | [Synthesis]
General procedure for the synthesis of 4-amino-1-isopropyl-1H-pyrazole from 1-isopropyl-4-nitro-1H-pyrazole: To a 25 mL round bottom flask was added a methanol solution (4 mL) of 1-isopropyl-4-nitro-1H-pyrazole (200 mg, 1.29 mmol, 1.00 equiv.) and palladium carbon (40 mg). Hydrogen (H2) was passed into the reaction system and the reaction was stirred for 3 hours at room temperature. Upon completion of the reaction, the solid catalyst was removed by filtration and the filtrate was concentrated in vacuum to afford 154 mg (95% yield) of 4-amino-1-isopropyl-1H-pyrazole as a pink oil. | [References]
[1] Patent: WO2015/48281, 2015, A1. Location in patent: Paragraph 00510; 00512
[2] Patent: US2015/336982, 2015, A1. Location in patent: Paragraph 0301; 0303
[3] Patent: WO2017/4134, 2017, A1. Location in patent: Paragraph 00293
[4] Patent: WO2006/40520, 2006, A1. Location in patent: Page/Page column 123-124
[5] Patent: WO2007/99326, 2007, A1. Location in patent: Page/Page column 112 |
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