| Identification | Back Directory | [Name]
DL-BUTHIONINE-SULFOXIMINE | [CAS]
97590-40-4 | [Synonyms]
(2S)-2-amino-4-(butylsulfonimidoyl)butanoic acid | [Molecular Formula]
C8H18N2O3S1 | [MOL File]
97590-40-4.mol | [Molecular Weight]
222.31 |
| Hazard Information | Back Directory | [Definition]
ChEBI: L-buthionine-(S,R)-sulfoximine is a 2-amino-4-(S-butylsulfonimidoyl)butanoic acid which has S-configuration. It is a inhibitor of gamma-glutamylcysteine synthetase and glutathione (GSH) biosynthesis and is capable of enhancing the apoptotic effects of several chemotherapeutic agents. It has a role as a ferroptosis inducer and an EC 6.3.2.2 (glutamate--cysteine ligase) inhibitor. |
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