| Identification | Back Directory | [Name]
2-ThiophenecarboxaMide, 5-chloro-N-Methyl- | [CAS]
97799-98-9 | [Synonyms]
Rivaroxaban K
Rivaroxaban impurity P2-S
Rivaroxaban CMTCA Impurity
5-Chloro-N-methylthiophene-2-carboxamide
2-Thiophenecarboxamide, 5-chloro-N-methyl-
5-chloro-2-thiophenecarboxylic acid N-methylamide
Rivaroxaban impurity N: 5-chlorothiophene-2-carboxamide
Imp. D:5-Chloro-2-Thiophenecarboxylic Acid N-Methylamide
2-ThiophenecarboxaMide, 5-chloro-N-Methyl- ISO 9001：2015 REACH
2-ThiophenecarboxaMide, 5-chloro-N-Methyl- ExperiMental Properties
Rivaroxaban Impurity 18/5-Chloro-2-Thiophenecarboxylic Acid N-Methylamide
Rivaroxaban Related Compound (5-Chloro-2-Thiophenecarboxylic Acid N-Methylamide) | [Molecular Formula]
C6H6ClNOS | [MDL Number]
MFCD00508500 | [MOL File]
97799-98-9.mol | [Molecular Weight]
175.64 |
| Chemical Properties | Back Directory | [Melting point ]
164-166°C | [storage temp. ]
Refrigerator | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
5-Chloro-N-methylthiophene-2-carboxamide is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor. | [Synthesis]
Step ① add 5-chlorothiophene-2-carboxylic acid, dichloromethane, dichlorosulfoxide dropwise at 0 ℃, dropwise addition, room temperature stirring for 4 hours; Step ② dropwise addition of aqueous solution with a mass concentration of 40% of methyla |
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| Company Name: |
BOC Sciences
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16314854226 |
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www.bocsci.com |
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