| Identification | Back Directory | [Name]
1-Amino-1-cyclobutanecarboxylic acid hydrochloride | [CAS]
98071-16-0 | [Synonyms]
1-aMino-
H-AC4C-OH*HCl
1-AMinocyclobutane
1-AminocyclobutanecarboxlicacidHCl
cyclobutanecarboxylic acid, 1-amino-
1-Aminocyclobutanecarboxlicacidmonohydrochloride
AMino-1-cyclobutanecarboxylic acid hydrochloride
1-AminocyclobutanecarboxylicAcidHydrochloride,98%
1-AMINO CYCLOBUTANE CARBOXYLIC ACID HYDROCHLORIDE
1-aMinocyclobutane-1-carboxylic acid hydrochloride
1-Amino-1-cyclobutanecarboxylic acid hydrochloride
1-Aminocyclobutanecarboxylic Acid Hydrochloride >
Cyclobutanecarboxylic acid, 1-amino-, hydrochloride
1-Amino-1-cyclobutanecarboxylic acid hydrochloride(For export only) | [EINECS(EC#)]
619-316-0 | [Molecular Formula]
C5H10ClNO2 | [MDL Number]
MFCD08752285 | [MOL File]
98071-16-0.mol | [Molecular Weight]
151.591 |
| Chemical Properties | Back Directory | [Melting point ]
226 °C | [RTECS ]
GU1336000 | [storage temp. ]
Room temperature. | [Water Solubility ]
Soluble in water | [form ]
Powder | [color ]
White to Almost white | [InChI]
InChI=1S/C5H9NO2.ClH/c6-5(4(7)8)2-1-3-5;/h1-3,6H2,(H,7,8);1H | [InChIKey]
HBTVGNDTGRUBQO-UHFFFAOYSA-N | [SMILES]
C1(N)(C(O)=O)CCC1.[H]Cl |
| Hazard Information | Back Directory | [Uses]
NMDA receptor antagonist acting at the glycine site | [Application]
1-Aminocyclobutanecarboxylic Acid Hydrochloride is an essential organic synthesis reagent with good chemical stability and ease of use. It is widely used in organic synthesis and medicinal chemistry, helping to prepare complex organic molecules, including peptide chains, drugs, and four-membered ring bioactive molecules. This substance can be used in synthesizing polypeptides and can be used to activate amino acids to form peptide bonds. It is widely used in pharmaceutical synthesis to synthesize drug intermediates, especially drug molecules containing amino acid residues. It can be used to construct the skeleton structure of biologically active molecules.
| [Synthesis]
Ethyl 1-aminocyclobutanecarboxylate (1.0 g, 6.28 mmol) was dissolved in 1N HCl (10 ml) in a dry reaction flask and the resulting reaction mixture was heated to reflux and stirred at reflux for about 2 hours. The progress of the reaction was monitored by T |
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