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98092-14-9

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98092-14-9 Structure

98092-14-9 Structure
IdentificationBack Directory
[Name]

ISOVALERYL-PHE-NLE-STA-ALA-STA-OH
[CAS]

98092-14-9
[Synonyms]

SR 42128
Iva-Phe-Nle-Sta-Ala-Sta-OH
ISOVALERYL-PHE-NLE-STA-ALA-STA-OH
N-(3-Methyl-1-oxobutyl)-L-phenylalanyl-L-norleucyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-L-alaninamide
L-Alaninamide, N-(3-methyl-1-oxobutyl)-L-phenylalanyl-L-norleucyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-
[Molecular Formula]

C39H65N5O9
[MDL Number]

MFCD00238289
[MOL File]

98092-14-9.mol
[Molecular Weight]

747.96
Chemical PropertiesBack Directory
[storage temp. ]

-15°C
[Sequence]

{Isovaleryl}-Phe-{Nle}-{Sta}-Ala-{Sta}
Hazard InformationBack Directory
[Uses]

SR 42128 is a potent renin inhibitor. SR 42128 potently inhibits primate renins whereas other animal renins are much less inhibited[1].
[References]

[1] M De Claviere, et al. In vitro and in vivo inhibition of human and primate renin by a new potent renin inhibitor: SR 42128. J Cardiovasc Pharmacol. 1985:7 Suppl 4:S58-61. DOI:10.1097/00005344-198507004-00012
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