| Identification | Back Directory | [Name]
1-(p-Fluoro-phenyl-6-fluoro-7-chloro-4-oxo-3-quinolinecarboxylic acid | [CAS]
98105-79-4 | [Synonyms]
Difloxacin impurity G
Difloxacin EP Impurity G
Difloxacin EP Impurituy G
7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-3-quinolinecarboxylic acid
1-(p-Fluoro-phenyl-6-fluoro-7-chloro-4-oxo-3-quinolinecarboxylic acid
1-4(4-FLUOROPHENYL)-6-FLUORO-7-CHLORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3- C ARBOXYLIC
1-(4-Fluorophenyl)-6-fluoro-7-chloro-1,4-dihydro-4-oxoquinoline-3-carboxylicacid
7-CHLORO-6-FLUORO-1-(4-FLUOROPHENYL)-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLIC ACID
7-Chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
3-Quinolinecarboxylic acid, 7-chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo- | [Molecular Formula]
C16H8ClF2NO3 | [MDL Number]
MFCD04153757 | [MOL File]
98105-79-4.mol | [Molecular Weight]
335.69 |
| Chemical Properties | Back Directory | [Melting point ]
260-264℃ | [Boiling point ]
514℃ | [density ]
1.584 | [Fp ]
265℃ | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
neat | [Major Application]
pharmaceutical (small molecule) | [InChI]
1S/C16H8ClF2NO3/c17-12-6-14-10(5-13(12)19)15(21)11(16(22)23)7-20(14)9-3-1-8(18)2-4-9/h1-7H,(H,22,23) | [InChIKey]
FBAMWRYINJFGPJ-UHFFFAOYSA-N | [SMILES]
Fc1ccc(cc1)[n]2c3c([c](c(c2)C(=O)O)=O)cc(c(c3)Cl)F |
| Hazard Information | Back Directory | [Uses]
7-Chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid is a 1-arylated derivative of 1,4-dihydro-4-oxoquinoline-3-carboxylic acid with antibacterial activity. | [Synthesis]
1-(p-Fluoro-phenyl)-6-fluoro-7-chloro-4-oxo-3-quinolinecarboxylic acid was synthesised by a three-step procedure. Step 1: Preparation of 2,4-dichloro-5-fluoroacetophenone. 2,4-Dichlorofluorobenzene undergoes a Friedel-Crafts reaction with AcCl catalyzed b |
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