| Identification | Back Directory | [Name]
Benzyl-PEG3-Tos | [CAS]
98627-22-6 | [Synonyms]
Benzyl-PEG3-Tos
2-(2-(benzyloxy)ethoxy)ethyl 4-methylbenzenesulfonate
2-<2-(phenylmethoxy)ethoxy>ethanol 4-methylbenzenesulfonate
Ethanol, 2-[2-(phenylmethoxy)ethoxy]-, 4-methylbenzenesulfonate
Ethanol, 2-[2-(phenylmethoxy)ethoxy]-, 4-methylbenzenesulfon...
2-(2-(benzyloxy)ethoxy)ethyl 4-methylbenzenesulfonate(WXC06918)
Ethanol, 2-[2-(phenylmethoxy)ethoxy]-, 1-(4-methylbenzenesulfonate) | [Molecular Formula]
C18H22O5S | [MDL Number]
MFCD28064331 | [MOL File]
98627-22-6.mol | [Molecular Weight]
350.43 |
| Hazard Information | Back Directory | [Description]
Benzyl-PEG3-Tos is a PEG linker with an acid labile, benzyl protecting group. The tosyl group is a good leaving group. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | [Uses]
Benzyl-PEG2-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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