| Identification | Back Directory | [Name]
Butanedioic acid, 2-hexylidene-3-methyl-, (2E)- | [CAS]
98985-76-3 | [Synonyms]
Piliformic Acid
Butanedioic acid, 2-hexylidene-3-methyl-, (2E)- | [Molecular Formula]
C11H18O4 | [MOL File]
98985-76-3.mol | [Molecular Weight]
214.26 |
| Chemical Properties | Back Directory | [Melting point ]
155 °C(Solv: water (7732-18-5)) | [Boiling point ]
399.8±25.0 °C(Predicted) | [density ]
1.109±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
A solid | [pka]
3.96±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Piliformic acid is a fungal metabolite found in the endophytic fungus Xylariasp sp.(No. 2508) from mangrove trees from the coast of the South China Sea[1]. | [Biological Activity]
Piliformic acid is a fungal metabolite that has been found in N. pseudotrichia and has diverse biological activities.1,2 It is cytotoxic to BC-1 human breast cancer cells (IC50 = 5 μg/ml).2 Piloformic acid is active against L. braziliensis amastigotes (IC50 = 78.5 μM). It is also active against the plant pathogenic fungi C. gloeosporioides (MIC = 292 μM).1 | [References]
1.Elias, L.M., Fortkamp, D., Sartori, S.B., et al.The potential of compounds isolated from Xylaria spp. as antifungal agents against anthracnoseBraz. J. Microbiol.49(4)840-847(2018)
2.Cota, B.B., Tunes, L.G., Maia, D.N.B., et al.Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood)Mem. Inst. Oswaldo Cruz113(2)102-110(2018)
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