| Identification | Back Directory | [Name]
GLY-LYS-GLY-ARG-GLY-LEU-SER-LEU-SER-ALA-PHE-SER-TRP-GLY-ALA | [CAS]
99026-78-5 | [Synonyms]
[ALA113]-MBP (104-118)
[ALA113]-MBP FRAGMENT 104-118
[Ala113]-Myelin Basic Protein (104-118)
[ALA113]-MYELIN BASIC PROTEIN FRAGMENT 104-118
GLY-LYS-GLY-ARG-GLY-LEU-SER-LEU-SER-ALA-PHE-SER-TRP-GLY-ALA
(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-6-amino-2-[(2-aminoacetyl)amino]hexanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]acetyl]amino]propanoic acid | [Molecular Formula]
C67H104N20O19 | [MDL Number]
MFCD00273541 | [MOL File]
99026-78-5.mol | [Molecular Weight]
1493.67 |
| Chemical Properties | Back Directory | [density ]
1.45±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Soluble to 2 mg/ml in 0.25% acetic acid | [form ]
lyophilized powder
| [pka]
3.42±0.10(Predicted) | [Sequence]
H-Gly-Lys-Gly-Arg-Gly-Leu-Ser-Leu-Ser-Ala-Phe-Ser-Trp-Gly-Ala-OH |
| Hazard Information | Back Directory | [Uses]
[Ala113]MBP(104-118) is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM[1]. | [IC 50]
PKC: 28-62 μM (IC50) | [storage]
Desiccate at -20°C | [References]
[1] Su HD, et, al. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C). Biochem Biophys Res Commun. 1986 Jan 14; 134(1): 78-84. DOI:10.1016/0006-291x(86)90529-2 |
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BOC Sciences
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https://www.bocsci.com |
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