ChemicalBook--->CAS DataBase List--->99120-49-7

99120-49-7

99120-49-7 Structure

99120-49-7 Structure
IdentificationBack Directory
[Name]

GLP-2 (HUMAN)
[CAS]

99120-49-7
[Synonyms]

GLP-2
glp-2-arg
GLP-2 (1-34)
GLP-2 (HUMAN)
GLP-2 (1-33) (HUMAN)
GLP-2 (1-34) (HUMAN)
Preproglucagon 126-159
GLP-2 (HUMAN) USP/EP/BP
GLUCAGON-LIKE PEPTIDE-2
GLUCAGON-LIKE PEPTIDE II HUMAN
GLUCAGON-LIKE PEPTIDE 2 (HUMAN)
PREPROGLUCAGON (126-159) (HUMAN)
PREPROGLUCAGON (146-178) (HUMAN)
HADGSFSDEMNTILDNLAARDFINWLIQTKITDR
GLUCAGON-LIKE PEPTIDE 2 ARG (HUMAN)
GLP-2-Arg, Preproglucagon 126-159
Glucagon-Like Peptide II, (1-34), human
GLP-2-ARG (HUMAN) TRIFLUOROACETATE SALT
PREPROGLUCAGON (146-179) (HUMAN) TRIFLUOROACETATE SALT
glucagon-like peptide 2 -arg human trifluoroacetate salt
Glucagon-Like Peptide II, human HADGSFSDEMNTILDNLAARDFINWLIQTKITDR
Glucagon-Like Peptide 2 -Arg human trifluoroacetate salt >90% (HPLC), solid
Proglucagon (126-159) (huMan), Preproglucagon (146-179) (huMan), Glucagon-Like Peptide 2-Arg (huMan)
GLP-2 (1-34) (huMan) Proglucagon (126-159) (huMan), Preproglucagon (146-179) (huMan), Glucagon-Like Peptide 2-Arg (huMan)
HIS-ALA-ASP-GLY-SER-PHE-SER-ASP-GLU-MET-ASN-THR-ILE-LEU-ASP-ASN-LEU-ALA-ALA-ARG-ASP-PHE-ILE-ASN-TRP-LEU-ILE-GLN-THR-LYS-ILE-THR-ASP
HIS-ALA-ASP-GLY-SER-PHE-SER-ASP-GLU-MET-ASN-THR-ILE-LEU-ASP-ASN-LEU-ALA-ALA-ARG-ASP-PHE-ILE-ASN-TRP-LEU-ILE-GLN-THR-LYS-ILE-THR-ASP-ARG
H-HIS-ALA-ASP-GLY-SER-PHE-SER-ASP-GLU-MET-ASN-THR-ILE-LEU-ASP-ASN-LEU-ALA-ALA-ARG-ASP-PHE-ILE-ASN-TRP-LEU-ILE-GLN-THR-LYS-ILE-THR-ASP-OH
H-HIS-ALA-ASP-GLY-SER-PHE-SER-ASP-GLU-MET-ASN-THR-ILE-LEU-ASP-ASN-LEU-ALA-ALA-ARG-ASP-PHE-ILE-ASN-TRP-LEU-ILE-GLN-THR-LYS-ILE-THR-ASP-ARG-OH
HIS-ALA-ASP-GLY-SER-PHE-SER-ASP-GLU-MET-ASN-THR-ILE-LEU-ASP-ASN-LEU-ALA-ALA-ARG-ASP-PHE-ILE-ASN-TRP-LEU-ILE-GLN-THR-LYS-ILE-THR-ASP-ARG: HADGSFSDEMNTILDNLAARDFINWLINTKITDR
[Molecular Formula]

C171H266N48O56S1
[MDL Number]

MFCD00081649
[Molecular Weight]

3922.29
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

solid
[Sequence]

His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-Arg
Safety DataBack Directory
[Safety Statements ]

22-24/25
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Glucagon-Like Peptide 2 (GLP-2) -Arg human trifluoroacetate salt has been used for injection in chickens to determine the effects of GLP-2 on the weight and morphology of small intestines.
[General Description]

Glucagon-like peptide 2 (GLP-2) is a member of the pro-glucagon gene family which is released in small and large intestinal circulation by enteroendocrine L cells. This peptide is composed of 33 amino acids.
[Biochem/physiol Actions]

Glucagon-like peptide 2 (GLP-2) influences the functionality of gastrointestinal tract by participating in the feedback loop to the brain for the control of food intake. It also controls digestion and absorption, and has tropic effects post chemotherapy injury or surgical resection. This peptide is also responsible for epithelial cell proliferation of the small bowel. Studies in rats show that this peptide enhances the effects of the ileal-brake hormones, GLP-1 and peptide YY. It also negatively regulates gastrointestinal motility and secretion. Thus, it has potential as a therapeutic agent in short-bowel syndrome.
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