| Identification | Back Directory | [Name]
5-bromo-3-phenyl Salicylic Acid | [CAS]
99514-99-5 | [Synonyms]
HUQWWRUNBHYQLK-UHFFFAOYSA-N
3-phenyl-5-bromosalicylic acid
5-bromo-3-phenyl Salicylic Acid
5-bromo-2-hydroxy-[1,1'-biphenyl]-3-carboxylicacid
5-Bromo-2-hydroxy[1,1'-biphenyl]-3-carboxylic acid
[1,1'-Biphenyl]-3-carboxylic acid, 5-bromo-2-hydroxy-
5 bromo 3 phenyl Salicylic Acid,5bromo3phenyl Salicylic Acid | [Molecular Formula]
C13H9BrO3 | [MOL File]
99514-99-5.mol | [Molecular Weight]
293.11 |
| Chemical Properties | Back Directory | [Boiling point ]
416.9±45.0 °C(Predicted) | [density ]
1.611±0.06 g/cm3(Predicted) | [solubility ]
DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 20 mg/ml; Ethanol: 3 mg/ml | [form ]
A crystalline solid | [pka]
2.38±0.14(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
5-Bromo-3-phenyl salicylic acid is a selective inhibitor for human 20α-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 140 nM[1]. | [References]
[1] El-Kabbani O, et al., Structure-guided design, synthesis, and evaluation of salicylic acid-based inhibitors targeting a selectivity pocket in the active site of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1). J Med Chem. 2009 May 28;52(10):3259-64. DOI:10.1021/jm9001633 |
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
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