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99782-89-5

99782-89-5 Structure

99782-89-5 Structure
IdentificationBack Directory
[Name]

Mevastatin Hydroxy Acid SodiuM Salt
[CAS]

99782-89-5
[Synonyms]

Reaxys ID: 5700835
ML 236B SodiuM Salt
Mevastatin Hydroxy Acid SodiuM Salt
(βR,δR,1S,2S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2-Methyl-8-[(2S)-2-Methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid SodiuM Salt
(βR,δR,1S,2S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2-Methyl-8-[(2S)-2-Methyl-1-oxobutoxy]-1-naphthaleneheptanoic Acid MonosodiuM Salt
[1S-[1α(βS*,δS*),2α,8β(R*),8aα]]-1,2,6,7,8,8a-Hexahydro-β,δ-dihydroxy-2-Methyl-8-(2-Methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid MonosodiuM Salt
[Molecular Formula]

C23H35NaO6
[MOL File]

99782-89-5.mol
[Molecular Weight]

430.51
Chemical PropertiesBack Directory
[Melting point ]

>143°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
[form ]

White to off-white solid.
[color ]

White to Light Grey
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

An active carboxylate of Mevastatin (M340500). It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood.
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