102029-73-2
基本信息
乙醯COA
乙酰COA
乙酰辅酶 A
乙酰辅酶A钠
乙酰辅酶A三钠盐
乙酰辅酶 A 钠盐
乙酰辅酶A钠盐(进分)
乙酰辅酶 A(乙酰辅酶 A 钠盐)
ACETYL COENZYME A 钠盐
acetyl coa
Acetyl-S- CoA
Acetyl-Coenzym A
ACETYL COENZYME A
Acetyl Coenzyme A trisodium
ACETYL COENZYME A SODIUM SALT
ACETHYL COENZYME A SODIUM SALT
Acethyl coenzyme alpha sodium salt
Acetyl coenzyme A sodium salt,Acetyl CoA
常见问题列表
A2-ATF1,乙酸乙酯含量分别为72.52 mg/L和44.80 mg/L,分别是单独过表达ATF1基因a5-ATF1的204.14%和125.67%,且ΔA-ATF1比α5-ATF1产乙酸乙酯显著增加,结果表明,在底物乙酰辅酶A充足的条件下,提高醇乙酰基转移酶活性,能够提高乙酸乙酯的生成量。
Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant molecule constituted by an acetyl moiety (CH3CO) linked to coenzyme A (CoA), a derivative of vitamin B5 and cysteine, through a thioester bond. As thioester bonds are energy rich, the chemical structure of acetyl-CoA facilitates the transfer of the acetyl moiety to a variety of acceptor molecules, including amino groups on proteins.
In most mammalian cells, Acetyl-coenzyme A (Acetyl-CoA) is predominantly generated in the mitochondrial matrix by various metabolic circuitries, namely glycolysis, β-oxidation, and the catabolism of branched amino acids. Cytosolic Acetyl-coenzyme A is the precursor of multiple anabolic reactions that underlie the synthesis of fatty acids and steroids, as well as specific amino acids including glutamate, proline, and arginine.
Mice deprived of food (but with access to water ad libitum) for 24 hr exhibit a significant reduction in total Acetyl-coenzyme A (Acetyl-CoA) levels in several organs, including the heart and muscles, corresponding to a decrease in protein acetylation levels. However, the same experimental conditions have no major effects on Acetyl-coenzyme A concentrations in the brain and actually increase hepatic Acetyl-coenzyme A and protein acetylation levels. Ethanol intake augments Acetyl-coenzyme A levels in hepatic mitochondria.