1033040-23-1
中文名称
1033040-23-1
英文名称
TPO agonist 1
CAS
1033040-23-1
分子式
C25H22N8O2
分子量
466.49
MOL 文件
1033040-23-1.mol
1033040-23-1 结构式
基本信息
中文别名
化合物 T17146 英文别名
TPO agonist 11H-Pyrazole-4,5-dione, 1-(3,4-dimethylphenyl)-3-methyl-, 4-[2-[2-hydroxy-3'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]hydrazone]
物理化学性质
沸点703.5±70.0 °C(Predicted)
密度1.42±0.1 g/cm3(Predicted)
酸度系数(pKa)4.25±0.10(Predicted)
形态Solid
颜色Pink to red
1033040-23-1价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-100380 | 1033040-23-1 TPO agonist 1 | 1033040-23-1 | 2mg | 1000元 |
| 2025/05/22 | HY-100380 | 1033040-23-1 TPO agonist 1 | 1033040-23-1 | 5mg | 1400元 |
| 2025/05/22 | HY-100380 | 1033040-23-1 TPO agonist 1 | 1033040-23-1 | 10mM * 1mLin DMSO | 1437元 |
常见问题列表
生物活性
TPO agonist 1 是一种 TPO 激动剂，可用作血小板生成和巨核细胞生成的促进剂，可用于血小板减少症的研究。详细信息请参考专利文献 WO2008134338A1 中的化合物 TPO mimetic。靶点
TPO receptor
体内研究
The thrombopoietin (TPO) receptor agonists are novel treatments for patients with chronic ITP aimed at increasing platelet production through interactions with the TPO receptor on megakaryocytes, and can increases platelet counts, decrease bleeding events and reduce the need for adjunctive or rescue treatments. The TPO receptor agonists are well-tolerated, though uncertainty remains regarding the risk of thromboembolism and bone marrow fibrosis.