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1135-23-5

中文名称 磷酸异丙酯(单双酯混合物)
英文名称 3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID
CAS 1135-23-5
EINECS 编号 214-489-5
分子式 C10H12O4
MDL 编号 MFCD00016558
分子量 196.2
MOL 文件 1135-23-5.mol
更新日期 2024/04/24 17:29:42
1135-23-5 结构式 1135-23-5 结构式

基本信息

中文别名
磷酸异丙酯(单双酯混合物)
3-(4-羟基甲基)丙酸
氢化阿魏酸
3-(4-羟基-3-甲氧基苯基)丙酸
英文别名
3-(3-METHOXY-4-HYDROXYPHENYL)-PROPIONIC ACID
3-(4-HYDROXY-3-METHOXYPHENYL)PROPANOIC ACID
3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID
3-(4-HYDROXYMETHYL)PROPIONIC ACID
3-METHOXY-4-HYDROXYHYDROCINNAMIC ACID
4-HYDROXY-3-METHOXYHYDROCINNAMIC ACID
BETA-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID
HYDROFERULIC ACID
Benzenepropanoic acid, 4-hydroxy-3-methoxy-
3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC
HYDROFERULIC ACID(RG)
3-(4-HYDROXY-3-METHOXYPHENYL)PROPIONIC ACID 98%
3-Methoxy-4-hydroxybenzenepropanoic acid
3-Methoxy-4-hydroxybenzenepropionic acid
4-Hydroxy-3-methoxybenzenepropanoic acid
所属类别
香精与香料:芳香肉桂酸、酯及衍生物

物理化学性质

熔点87-93 °C
沸点120-130 °C(Press: 0.5 Torr)
密度1.259±0.06 g/cm3(Predicted)
溶解度溶于二甲基亚砜和甲醇。
酸度系数(pKa)4.73±0.10(Predicted)
形态粉末晶体
颜色白色至浅黄色
BRN2110370
LogP0.810 (est)

安全数据

危险性符号(GHS)
GHS07
警示词警告
危险性描述H302-H315-H319-H335
危险品标志Xn
危险类别码R22-R36/37/38
安全说明S26-S36
WGK Germany2
危险等级IRRITANT
海关编码29189900
磷酸异丙酯(单双酯混合物)价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/01/16A120693-(4-羟基-3-甲氧基苯基)丙酸, 97%
3-(4-Hydroxy-3-methoxyphenyl)propionic acid, 97%
1135-23-51g830元
2024/01/16A120693-(4-羟基-3-甲氧基苯基)丙酸, 97%
3-(4-Hydroxy-3-methoxyphenyl)propionic acid, 97%
1135-23-55g3197元
2024/01/16H11803-(4-羟基-3-甲氧苯基)丙酸
3-(4-Hydroxy-3-methoxyphenyl)propionic Acid
1135-23-51G350元

常见问题列表

生物活性
Dihydroferulic acid (Hydroferulic acid) 是姜黄素的主要代谢产物之一,具有抗氧化/清除自由基的活性,IC50 值为 19.5 μM。Dihydroferulic acid 是人类肠道菌群的代谢产物,也是香草酸的前体物质。
体外研究

Uptake of hydroxycinnamic acids by control, organic anion transporter 1 (OAT1), OAT2, OAT3, and OAT4 over expressing 293H cells. In 293H control cells, there was significant uptake of Dihydroferulic acid. The uptake of Dihydroferulic acid is also enhanced ~2-fold in the OAT1-expressing cells.

体内研究

Assessing the influence of an 11 weeks intervention with a resistant starch-enriched whole grain diet (HI-RS-WG, 25% RS) compared to a WG control diet (LOW-RS-WG, 6.9% RS) on serum profile of polyphenols (PPs) in 20 Zucker Diabetic Fatty rats. Five PPs were identified and quantified in serum samples of rats belonging to both intervention groups. HI-RS-WG rats had 2.6 folds higher serum concentrations of total PPs than LOW-RS-WG rats. An explorative data reduction approach, based on the Principal Component Analysis identified two principal components related to the gut microbiota fermentation and food intake, respectively. Results showed that the abundance of hippuric acid and Dihydroferulic acid in HI-RS-WG rats was explained by the stronger gut microbiota fermentation in those rats than in LOW-RS-WG rats.

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