115453-99-1
115453-99-1 结构式
基本信息
中文别名
6-(4-氨基苯乙烯基)吡啶-2-羧酸 英文别名
CB-7921220CB-7921220 (CB7921220)
6-(4-Aminostyryl)picolinic acid
2-Pyridinecarboxylic acid, 6-[2-(4-aminophenyl)ethenyl]-
物理化学性质
熔点225-226 °C
沸点504.3±50.0 °C(Predicted)
密度1.329±0.06 g/cm3(Predicted)
储存条件Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度DMF: 30 mg/ml; DMSO: 30 mg/ml; PBS (pH 7.2): 0.3 mg/ml
酸度系数(pKa)1.01±0.50(Predicted)
形态A crystalline solid
颜色Pink to red
115453-99-1价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-101862 | 115453-99-1 CB-7921220 | 115453-99-1 | 2mg | 500元 |
| 2025/02/08 | HY-101862 | 115453-99-1 CB-7921220 | 115453-99-1 | 10mM * 1mLin DMSO | 661元 |
| 2025/02/08 | HY-101862 | 115453-99-1 CB-7921220 | 115453-99-1 | 5mg | 990元 |
常见问题列表
生物活性
CB-7921220是腺苷酸环化酶 (adenylate cyclase) 的抑制剂。体外研究
CB-7921220 shows a degree of isoform selectivity for adenylate cyclase (AC) 1, but cannot distinguish between AC1 and AC6. CB-7921220 has a more consistent predicted binding position in the two virtual docking screens, and has a binding conformation similar to ATP and P-site inhibitors, which may explain its lack of selectivity between AC1 and AC6.