1229018-87-4
中文名称
TPN171
英文名称
TPN171
CAS
1229018-87-4
分子式
C24H35N5O3
分子量
441.57
MOL 文件
1229018-87-4.mol
更新日期
2025/11/26 17:28:24
1229018-87-4 结构式
物理化学性质
密度1.20±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)8.78±0.50(Predicted)
形态Solid
颜色White to off-white
应用领域
用途一
TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6. TPN171 is a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension. TPN171 was proven to exert a longer lasting effect than sildenafil in animal models, providing a foundation for a once-daily oral administration for its clinical use.