1289942-55-7
中文名称
1289942-55-7
英文名称
4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-
CAS
1289942-55-7
分子式
C20H18F4N4O2
分子量
422.38
MOL 文件
1289942-55-7.mol
1289942-55-7 结构式
基本信息
中文别名
恩扎卢胺杂质A恩杂鲁胺杂质W
恩杂鲁胺杂质19
英文别名
Enzalutamide Impurity WEnzalutamide Impurity 26
4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-
物理化学性质
沸点616.2±55.0 °C(Predicted)
密度1.36±0.1 g/cm3(Predicted)
溶解度DMSO (Slightly), Methanol (Slightly)
酸度系数(pKa)13?+-.0.70(Predicted)
形态Solid
颜色White to Off-White
应用领域
用途一
4-[[2-[[4-Cyano-3-(trifluoromethyl)phenyl]amino]-1,1-dimethyl-2-oxoethyl]amino]-2-fluoro-N-methyl-benzamide is an impurity of Enzalutamide (M199800), an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.