13153-27-0
13153-27-0 结构式
基本信息
NBTGR
6-(4-nitrobenzylthio)guanosine
S-(P-NITROBENZYL)-6-THIOGUANOSINE
S-(4-NITROBENZYL)-6-THIOGUANOSINE
S-(4-Nitrobenzyl)-6-thioguanosine,99%
2-Amino-6-[(4-nitrobenzyl)thio]-9-β-D-ribofuranosylpurine
2-AMINO-6-[(4-NITROBENZYL)THIO]-9-BETA-D-RIBOFURANOSYLPURINE
S-(4-NITROBENZYL)-6-THIOGUANOSINE (NBTG) POTENT ADENOSINE TRAN
NBTG, NBTGR, 2-Amino-6-[(4-nitrobenzyl)thio]-9-β-D-ribofuranosylpurine
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-108322 | 6-(4-硝基苄硫醇)鸟苷 NBTGR | 13153-27-0 | 5mg | 1220元 |
| 2025/05/22 | HY-108322 | 6-(4-硝基苄硫醇)鸟苷 NBTGR | 13153-27-0 | 10 mM * 1 mLin DMSO | 1342元 |
| 2025/05/22 | HY-108322 | 6-(4-硝基苄硫醇)鸟苷 NBTGR | 13153-27-0 | 10 mg | 2000元 |
常见问题列表
Ki: 70 nM (adenosine uptake)
A group of purine ribonucleosides with alkarylmercapto substituents at the purine 6-position are potent inhibitors of several aspects of nucleoside metabolism that involved the transfer of ribosyl groups. NBTGR is one of the compounds that inhibits nucleoside transport by human erythrocytes; initial rates of uridine uptake are reduced to zero upon exposure of cells to 1 μM NBTGR. The inhibitor is firmly bound because repeated washing cannot restore uridine transport capability to NBTGR-treated cells. NBTGR inhibits the influx of uridine, inosine, and cytidine, without inhibiting the uptake of the corresponding bases, or that of D-glucose or L-leucine. Uridine antagonizes the NBTGR inhibition of uidine transport in a concentration-dependent manner. NBTGR and related compounds appear to interact with the mechanism for the facilitated transport of nucleosides.