1354945-69-9
中文名称
替格瑞洛中间体1脱保护杂质
英文名称
2-[[(3aR,4S,6R,6aS)-6-(7-azanyl-5-propylsulfanyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol
CAS
1354945-69-9
分子式
C17H26N6O4S
分子量
410.491
MOL 文件
1354945-69-9.mol
更新日期
2024/04/19 16:07:42
1354945-69-9 结构式
基本信息
中文别名
替卡格雷杂质7替格瑞洛杂质59
替格格雷杂质32
替格瑞洛相关化合物59
替格瑞洛中间体1脱保护杂质
替格瑞洛杂质8:中1脱保护
替格瑞洛杂质E:氯代合环杂质
(1S,2S,3R,5S)-3-(7-氯-5-(丙硫基)-3H-[1,2,3]三唑并[4,5-D]嘧啶-3-基)-5-(2-羟基乙氧基)环戊烷-1,2-二醇
(1S,2S,3R,5S)-3-[7-氯-5-(丙基硫基)-3H-[1,2,3]三唑并[4,5-D]嘧啶-3-基]-5-(2-羟基乙氧基)环戊烷-1,2-二醇
英文别名
Ticagrelor Related Compound 59Ticagrelor Impurity E: Chlorocyclic Impurity
(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)
2-[[(3aR,4S,6R,6aS)-6-(7-azanyl-5-propylsulfanyl-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol
所属类别
分析化学：药典标准品和杂质标准品应用领域
用途一
(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol is an intermediate in the synthesis of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.