136-16-3
中文名称
OXYTHIAMINE HYDROCHLORIDE
英文名称
OXYTHIAMINE HYDROCHLORIDE
CAS
136-16-3
分子式
C12H17Cl2N3O2S
分子量
338.25
MOL 文件
136-16-3.mol
更新日期
2025/05/09 10:45:41
136-16-3 结构式
基本信息
中文别名
化合物 T12354硫胺素(维生素B1)杂质19
英文别名
azoliumoxythiamin
oxythiamine
Hydroxythiamin
oxythiamine(1+)
OXYTHIAMINE HCL
OXYTHIAMINE HYDROCHLORIDE
Oxythiamine·HCl≥ 99% (assay)
Oxythiamine (Hydroxythiamin)
OXYTHIAMINE CHLORIDE HYDROCHLORIDE
物理化学性质
密度1.2416 (rough estimate)
折射率1.6740 (estimate)
储存条件−20°C
溶解度DMSO : 51.67 mg/mL (194.00 mM)
形态Solid
颜色White to off-white
OXYTHIAMINE HYDROCHLORIDE价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-107430 | Oxythiamine | 136-16-3 | 5 mg | 218元 |
| 2025/02/08 | HY-107430 | Oxythiamine | 136-16-3 | 10 mg | 350元 |
| 2025/02/08 | HY-107430 | OXYTHIAMINE HYDROCHLORIDE Oxythiamine | 136-16-3 | 10mM * 1mLin DMSO | 385元 |
常见问题列表
生物活性
Oxythiamine 是一种抗代谢物和维生素B1 (vitamin B1)拮抗剂，也是众所周知的硫铵 (thiamine) 拮抗剂和转酮醇酶 (transketolase) 抑制剂。靶点
Vitamin B1, Thiamine, Transketolase.
体外研究
Oxythiamine, an antimetabolite and a vitamin B1 antagonist, is a well-known thiamine antagonist and inhibitor of transketolase. Oxythiamine alters protein expression in a dose dependent manner. The level of alpha-enolase is increased by Oxythiamine treatment, while expression of 14-3-3 protein beta/alpha is suppressed by Oxythiamine at a stratified dose. Oxythiamine causes dynamic changes of total protein expression in time dependent fashion. Oxythiamine suppresses expression of cellular phosphor proteins significantly.