137004-80-9
中文名称
137004-80-9
英文名称
Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo-
CAS
137004-80-9
分子式
C25H35NO6S
分子量
477.61
MOL 文件
137004-80-9.mol
137004-80-9 结构式
基本信息
中文别名
化合物 T12404 英文别名
CCK-A receptor inhibitor 1Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo-
物理化学性质
沸点705.1±60.0 °C(Predicted)
密度1.187±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)4.47±0.10(Predicted)
常见问题列表
生物活性
CCK-A receptor inhibitor 1 是一种缩胆囊素 A (cholecystokinin A, CCK-A) 受体抑制剂，IC50 为 340 nM。靶点
IC50: 340 nM (CCK-A receptor)
体外研究
CCK-A receptor inhibitor 1 (Compound 7c) is a naphthyl sulfone derivative, which is synthesized and tested for cholecystokinin A (CCK-A) receptor inhibitory activity in order to study structure-activity relationships. Significant CCK-A receptor inhibitory activities are found in CCK-A receptor inhibitor 1 having very hydrophobic sidechains.