139889-53-5
中文名称
1R,2R-(+)-1-PHENYL-2-PALMITOYLAMINO-3-N-MORPHOLINE-1-PROPANOL;D-THREO-PPMP
英文名称
1R,2R-(+)-1-phenyl-2-palMitoylaMino-3-N-Morpholine-1-propanol
CAS
139889-53-5
分子式
C29H50N2O3
分子量
474.72
MOL 文件
139889-53-5.mol
139889-53-5 结构式
基本信息
英文别名
D-threo-PPMP (PPMP)1R,2R-(+)-1-phenyl-2-palMitoylaMino-3-N-Morpholine-1-propanol
N-[(1R,2R)-2-hydroxyl-1-(4-monopholinylmethyl)-2-phenylethyl]decanamid
1R,2R-(+)-1-PHENYL-2-PALMITOYLAMINO-3-N-MORPHOLINE-1-PROPANOL
D-THREO-PPMP
Hexadecanamide, N-[(1R,2R)-2-hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-
应用领域
用途一
D-threo-PPMP also known as 1R,2R-(+)-1-phenyl-2-palmitoylamino-3-N-morpholine-1-propanol, is a bioactive sphingolipid. It plays a vital role in regulation of ceramide metabolism. D-threo-PPMP influences cytokinesis failure and glycosylation by inhibiting glucosyl ceramide synthase (GCS). D-threo-PPMP also stops acylation reaction by inhibiting the activity of 1-O-acylceramide synthase (1-O-ACS).