14622-47-0
中文名称
地塞米松EP杂质I
英文名称
Dexamethasone Impurity I
CAS
14622-47-0
分子式
C22H28O5
分子量
372.45
MOL 文件
14622-47-0.mol
更新日期
2025/07/22 09:49:13
14622-47-0 结构式
基本信息
中文别名
地塞米松EP杂质I糠酸莫米松杂质23
地塞米松杂质杂质I
地塞米松杂质I(EP)
(9BETA,11BETA,16BETA)-17,21-二羟基-16-甲基-9,11-环氧孕甾-1,4-二烯-3,20-二酮
英文别名
DB11(16β-Methyl Epoxide)Dexamethasone-9(11)-alpha-Epoxide
Dexamethasone impurity 3/Dexamethasone EP Impurity I
Dexamethasone Impurity 9(Dexamethasone EP Impurity I)
17α,21-Dihydroxy-9β,11β-epoxy-16β-methyl-pregnadien-(1.4)-dion-(3.20)
(11α,16α)-9,11-Epoxy-17,21-dihydroxy-16-Methylpregna-1,4-diene-3,20-dione
(11a,16a)-9,11-Epoxy-17,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
Pregna-1,4-diene-3,20-dione, 9,11-epoxy-17,21-dihydroxy-16-methyl-, (11α,16α)-
16β-METHYL EPOXIDE(DB-11), 17α,21-DIHYDROXY-9β,11β,EPOXY-16β-METHYLPREGN-1,4-DIENE-3,20-DIONE
16BETA-METHYL EPOXIDE(DB-11): 17ALPHA,21-DIHYDROXY-9BETA,11BETA,EPOXY-16BETA-METHYLPREGN-1,4-DIENE-3,20-DIONE
所属类别
分析化学：药典标准品和杂质标准品物理化学性质
熔点>211°C
沸点564.9±50.0 °C(Predicted)
密度1.32±0.1 g/cm3(Predicted)
储存条件Refrigerator
溶解度DMSO (Slightly), Methanol (Slightly, Sonicated)
酸度系数(pKa)12.56±0.70(Predicted)
形态Solid
颜色White to Pale Red
InChIKeyGBDXNHBVYAMODG-HGBIFODKSA-N
SMILESC[C@]12C=CC(=O)C=C1CC[C@@]1([H])[C@]3([H])C[C@@H](C)[C@](O)(C(=O)CO)[C@@]3(C)C[C@H]3O[C@@]213