1620278-72-9
中文名称
TLR7/8激动剂1二盐酸盐
英文名称
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
CAS
1620278-72-9
分子式
C22H26ClN5
分子量
395.94
MOL 文件
1620278-72-9.mol
更新日期
2025/11/24 11:44:33
1620278-72-9 结构式
基本信息
中文别名
二盐酸TLR7/8 AGONIST 11-(4-(氨基甲基)苄基)-2-丁基-1H-咪唑并[4,5-C]喹啉-4-胺二盐酸盐
英文别名
TLR7/8 agonist-5d8 agonist 1 dihydrochloride
TLR7/8 Agonist 1 (hydrochloride)
TLR7/8 agonist 1 (dihydrochloride)
1-(4-(Aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride
所属类别
生物化工：生化试剂物理化学性质
储存条件-20°C储存
溶解度DMSO:83.33(Max Conc. mg/mL);192.72(Max Conc. mM)
形态固体
颜色Off-white to light yellow
InChIInChI=1S/C22H25N5.ClH/c1-2-3-8-19-26-20-21(17-6-4-5-7-18(17)25-22(20)24)27(19)14-16-11-9-15(13-23)10-12-16;/h4-7,9-12H,2-3,8,13-14,23H2,1H3,(H2,24,25);1H
InChIKeyIIFIHBPSMOIXGG-UHFFFAOYSA-N
SMILESC(C1C=CC(CN)=CC=1)N1C(=NC2C(N)=NC3=CC=CC=C3C1=2)CCCC.Cl
TLR7/8激动剂1二盐酸盐价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/05/22 | HY-103698A | TLR7/8激动剂1二盐酸盐 TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | 1 mg | 520元 |
| 2025/05/22 | HY-103698A | 1620278-72-9 TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | 10mM * 1mLin DMSO | 1237元 |
| 2025/05/22 | HY-103698A | 1620278-72-9 TLR7/8 agonist 1 dihydrochloride | 1620278-72-9 | 5mg | 1300元 |
常见问题列表
生物活性
TLR7/8 agonist 1 dihydrochloride 是一种 toll 样受体 TLR7/TLR8 的双重激动剂。靶点
TLR7/TLR8
体外研究
TLR7/8 agonist 1 (Compound 5d) shows prominent immunostimulatory activities. TLR7/8 agonist 1 serves as a convenient precursor for the covalent attachment of fluorophores without significant loss of activity. TLR7/8 agonist 1 retains TLR7-agonistic activity with an EC 50 of 20 nM. TLR7/8 agonist 1 (Compound 1) shows substantially different agonistic potencies in human TLR7 (50 nM) and TLR8 (55 nM) primary screens.