188696-80-2
188696-80-2 结构式
基本信息
中文别名
化合物 T14281 英文别名
AMP 397BecaMpanel
Becampanel (AMP 397)
Phosphonic acid, P-[[[(1,2,3,4-tetrahydro-7-nitro-2,3-dioxo-5-quinoxalinyl)methyl]amino]methyl]-
常见问题列表
生物活性
Becampanel (AMP397) 是有效的 AMPA 拮抗剂，也是一种抗癫痫药。体外研究
Becampanel is negative in a mouse lymphoma tk assay, which includes a 24 h treatment without S9. A weak micronucleus induction in vitro is found at the highest concentrations tested in V79 cells with S9.
体内研究
Becampanel is negative in the following in vivo studies, which includes the maximum tolerated doses of 320 mg/kg in mice and 2000 mg/kg in rats. Becampanel has no genotoxic potential in vivo.