18877-64-0
中文名称
L-氯化棕榈酰肉碱
英文名称
Palmitoyl-L-Carnitine Chloride
CAS
18877-64-0
分子式
C23H46ClNO4
分子量
436.07
MOL 文件
18877-64-0.mol
更新日期
2025/04/23 09:51:10
18877-64-0 结构式
基本信息
中文别名
氯化棕榈酰L-棕榈酰基肉碱
L-氯化棕榈酰肉碱
左旋棕榈酰肉碱盐酸盐
棕榈酰-L-肉碱盐酸盐
棕榈酰-L-肉碱氯化物
L-肉碱:盐酸盐,O-棕榈酰未标记
棕榈酰-L-肉碱盐酸盐
英文别名
Einecs 242-642-6L-CARNITINE:HCL, O-PALMITOYL
L-Palmitoylcarnitine chloride
PALMITOYL-L-CARNITINE CHLORIDE
O-PALMITOYL-L-CARNITINE CHLORIDE
HEXADECANOYL-L-CARNITINE CHLORIDE
Palmitoyl-L-carnitine hydrochloride
Palmitoyl-L-carnitine chloride≥ 99% (TLC)
(R)-3-(Palmitoyloxy)-4-(trimethylammonio)butanoate Hydrochloride
(R)-3-(Hexadecanoyloxy)-4-(trimethylammonio)butyrate Hydrochloride
所属类别
生物化工：碱基·核酸·衍生物物理化学性质
熔点168-172 °C(lit.)
储存条件−20°C
溶解度H2O: 25 mg/mL with heat or sonication
形态powder
颜色white
水溶解性H2O: 25mg/mL (with he at or sonication)
BRN4071005
CAS 数据库18877-64-0
L-氯化棕榈酰肉碱价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-113147A | L-氯化棕榈酰肉碱 L-Palmitoylcarnitine chloride | 18877-64-0 | 1 mg | 454元 |
| 2025/02/08 | HY-113147A | L-氯化棕榈酰肉碱 L-Palmitoylcarnitine chloride | 18877-64-0 | 5mg | 1000元 |
| 2025/02/08 | HY-113147A | L-氯化棕榈酰肉碱 L-Palmitoylcarnitine chloride | 18877-64-0 | 10 mM * 1 mLin DMSO | 1100元 |
常见问题列表
生物活性
L-Palmitoylcarnitine chloride是一种长链酰基肉碱和脂肪酸代谢产物，在缺血期间积聚于肌膜并扰乱膜脂环境。L-Palmitoylcarnitine chloride 通过与 Kir6.2 的相互作用抑制 KATP 通道活性，而不影响单通道电导。靶点
|
Kir6.2
|
Human Endogenous Metabolite
|
体外研究
L-Palmitoylcarnitine (1 µM) inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC
50
fell from 62 to 30 µM).
Modulation of the membrane lipid environment caused by L-Palmitoylcarnitine alters the K
ATP
channel function mainly through the interaction with endogenous PI cascade, especially PIP2.