1944-12-3
中文名称
氢溴酸非诺特罗
英文名称
FENOTEROL HYDROBROMIDE
CAS
1944-12-3
分子式
C17H22BrNO4
分子量
384.26
MOL 文件
1944-12-3.mol
更新日期
2023/03/20 15:41:19
1944-12-3 结构式
基本信息
中文别名
氢溴酸芬忒醇氢溴酸非诺特罗
氢溴酸菲诺特罗
菲诺特洛氢溴酸盐
氢溴酸非诺特罗 标准品
氢溴酸菲诺特罗标准溶液
甲醇中菲诺特罗溶液标准物质
非诺特罗峰鉴别 EP标准品
氢溴酸非诺特罗 EP标准品
氢溴酸非诺特罗/酚丙喘宁芬忒醇
英文别名
AirumEmitex
Ugacor
berotec
th1165a
Siobetec
Dosberotec
partusisten
FENOTEROL HBR
fenoterolbromide
所属类别
原料药：平喘药
氢溴酸非诺特罗价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-B0976A | 氢溴酸非诺特罗 Fenoterol hydrobromide | 1944-12-3 | 100mg | 700元 |
| 2024/04/30 | HY-B0976A | 氢溴酸非诺特罗 Fenoterol hydrobromide | 1944-12-3 | 10mM * 1mLin DMSO | 930元 |
| 2024/01/16 | S5768 | 氢溴酸非诺特罗 Fenoterol hydrobromide | 1944-12-3 | 25mg | 794.63元 |
常见问题列表
生物活性
Fenoterol hydrobromide (Phenoterol)是fenoterol的氢溴酸盐。Fenoterol是β2 adrenoreceptor激动剂，具有支气管扩张活性。靶点
| Target | Value |
|
β2 adrenoreceptor
() |
体外研究
Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.
Western Blot Analysis
| Cell Line: | THP-1 cells stimulated with AICAR |
| Concentration: | 1 μM |
| Incubation Time: | Pre-incubated 30 minutes |
| Result: | Significantly downregulated the elevated phosphorylation levels of AMPK. |
体内研究
Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.
| Animal Model: | Male C57BL/6J mice (6 weeks old) with neuropathy |
| Dosage: | 0.7 mg/kg |
| Administration: | Intraperitoneal injection; twice a day; for 3 weeks |
| Result: | Alleviated neuropathic allodynia during chronic treatment. |