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2642-98-0

中文名称 7-胺基去乙酰氧基头胞烷酸
英文名称 6-AMINOCHRYSENE
CAS 2642-98-0
EINECS 编号 220-149-7
分子式 C18H13N
MDL 编号 MFCD00003699
分子量 243.3
MOL 文件 2642-98-0.mol
2642-98-0 结构式 2642-98-0 结构式

基本信息

中文别名
7-胺基去乙酰氧基头胞烷酸
6-氨基屈
英文别名
6-AMINOCHRYSENE
6-CHRYSENAMINE
AMINOCHRYSENE
AMINOCHRYSENE, 6-
TIMTEC-BB SBB003194
6-Amc
Chrysenex
Chrysonex
ADCA
chrysen-6-ylamine
6-AMINOCHRYSENE 97% SUSPECTED CANCER AGENT
Chrysen-6-amine
Chrysene-12-amine
Crysonex
所属类别
化学试剂:三环化合物

物理化学性质

熔点209-211 °C(lit.)
沸点376.18°C (rough estimate)
密度0.8933 (rough estimate)
折射率1.4500 (estimate)
储存条件2-8°C
溶解度丙酮(微溶)、氯仿(微溶)、甲醇(微溶、加热)
酸度系数(pKa)4.32±0.30(Predicted)
形态固体
颜色黄色到棕色
水溶解性155ug/L(24 ºC)
Merck13,2275

安全数据

危险性符号(GHS)
GHS07
警示词警告
危险性描述H302
防范说明P301+P312+P330
危险品标志Xn
危险类别码R22
安全说明S45-S36/37/39-S26
WGK Germany3
RTECS号GC0500000
海关编码29214900

知名试剂公司产品信息

7-胺基去乙酰氧基头胞烷酸价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/01/25HY-1083157-胺基去乙酰氧基头胞烷酸
6-Aminochrysene
2642-98-025mg520元
2024/01/25HY-1083157-胺基去乙酰氧基头胞烷酸
6-Aminochrysene
2642-98-010mM * 1mLin DMSO572元
2024/01/25HY-1083157-胺基去乙酰氧基头胞烷酸
6-Aminochrysene
2642-98-050 mg800元

常见问题列表

生物活性
6-Aminochrysene (6-Aminochrysene) 是芳香胺类化合物,可用于脾肿大,骨髓性白血病和乳腺癌的研究。
体外研究

6-Aminochrysene inhibits the hydroxylation of aniline, 0-demethylation of p-nitroanisole, and N-demethylation of aminopyrine by rat liver microsomes. Pre-treatment of rats with 6-aminochrysene markedly decreases the N-demethylation in vitro but significantly increases the hydroxylation and the 0-demethylation.

体内研究

6-Aminochrysene is an inhibitor of the growth of several solid experimental tumours in vivo and has a cancerostatic effect on human breast cancer. Long term topical skin application of 6-Aminochrysene to mice induces development of benign skin tumors after 3 months and of skin malignancies after 7 months. Female mice respond earlier than males. Induction of skin tumors is more rapid when 6-Aminochrysene is applied ventrally instead of dorsally. Urinary excretion is about twice as high after skin application than after oral administration.

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