28874-58-0
28874-58-0 结构式
基本信息
二十二碳四烯酸
肾上腺酸(乙醇溶液)
肾上腺酸(溶解于乙醇)
廿二碳四烯酸 10MG
7,10,13,16-二十二碳四烯酸
顺式-7,10,13,16-二十二碳四烯酸
二十二碳四烯酸(顺-7,10,13,16)
DOCOSATETRAENOIC ACID
Adrenic Acid (22:4, n-6)
Adrenic Acid (Solution in ethanol)
7Z,10Z,13Z,16Z-DOCOSATETRAENOIC ACID
DOCOSA-7Z,10Z,13Z,16Z-TETRAENOIC ACID
DOCOSA-7Z,10Z,13Z,16Z-PENTAENOIC ACID
CIS-7,10,13,16-DOCOSA-TETRAENOIC ACID
(All-Z)-7,10,13,16-docosatetraenoic acid
CIS-7,10,13,16,19-DOCOSA-TETRAENOIC ACID
物理化学性质
常见问题列表
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Human Endogenous Metabolite
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Adrenic acid is produced via the elongation of arachidonic acid by ELOVL2 and 5. Interestingly, the hepatic level of free Adrenic Acid (22:4n6) is markedly higher in the CDAHFD-fed db/db mice than in the SD-fed db/db mice. In plasma, the difference in the adrenic acid level reaches statistical significance (p<0.001). It is also found that the concentrations of phospholipid species containing Adrenic Acid, such as PC or PE (40:4) (containing side chain 18:0/22:4), and LPC 22:4 (sn-1/sn-2), are also significantly increased. (sn-1/sn-2). The hepatic and plasma levels of Adrenic Acid, which is an omega 6 polyunsaturated fatty acid (PUFA), exhibit greater differences between the CDAHFD-fed db/db mice and the SD-fed db/db mice (8.6-fold higher vs. 1.6-fold higher in liver tissue, 5.3-fold higher vs. 2.2-fold higher in plasma) than those of well-known proinflammatory PUFA, such as Arachidonic Acid.