3200-06-4
3200-06-4 结构式
基本信息
草酸萘呋胺
萘呋胺草酸盐
草酸萘呋胺氢
萘呋胺酯草酸盐
硝基呋喃草酸氢盐
萘呋胺酯草酸盐 标准品
Α-(1-萘基甲基)-2-四氢呋喃丙酸二乙氨基乙酯
Α-(1-萘甲基)-2-四氢呋喃丙酸二乙胺基乙基酯草酸盐
alpha-(1-萘甲基)-2-四氢呋喃丙酸二乙胺基乙基酯草酸盐
Iridus
eu-1806
CLARANTIN
Acid oxalate
NAFRONYL OXALATE
naftidrofuryloxalate
Nafronyl acid oxalate
hylester,oxalate(1:1)
NAFRONYL OXALATE SALT
物理化学性质
常见问题列表
萘呋胺酯草酸盐为有机酸物质，其是脑血管和外周血管的扩张剂；拮抗5-羟色胺及缓激肽的作用；可使细胞内ATP增多以改善细胞代谢；降低血液及血浆的粘稠度及纤维蛋白原浓度；增加细胞的氧化能力，对细胞缺氧具保护作用；此外具有罂粟碱样的解痉作用，缓慢而持久。
萘呋胺酯草酸盐是一种用于治疗心脑血管与周围血管疾病的药物，具有如下特点：其扩张作用比烟酸强，增强脑血管流量的作用较罂粟缓慢而持久。据认为其临床应用比罂粟碱安全，对严重下肢动脉炎的疗效较烟胺羟丙茶碱显著而迅速。
萘呋胺酯草酸盐是一种用于治疗心脑血管与周围血管疾病的药物。其具有如下特点：其扩张作用比烟酸强，增强脑血管流量的作用较罂粟缓慢而持久。
| Target | Value |
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5-HT2 receptor
() |
Naftidrofuryl oxalate (Nafronyl oxalate salt) may be effective for relieving the pain of muscle cramps.
Naftidrofuryl oxalate (Nafronyl oxalate salt) is the only vasoactive drug for peripheral arterial disease (PAD) which is likely to be cost-effective.
Naftidrofuryl oxalate (Nafronyl oxalate salt) is ranked first for both maximum walking distance (MWD) and pain-free walking distance (PFWD) (probability of 0·947 and 0·987, respectively, of being the best treatment) followed by cilostazol and pentoxifylline. Naftidrofuryl oxalate (Nafronyl oxalate salt) is effective treatments for claudication, Naftidrofuryl oxalate is likely to be the most effective, with minimal serious adverse events.