基本信息
中文别名
1-氟-2-羟基丙烷-1,2,3-三羧酸 英文别名
Fluorocitric acidfluorocitrate
2-Fluoro-L-erythro-citrate
Erythrofluorocitrate (isomer)
14466-42-3 (Unspecified hydrochloride salt)
3-C-Carboxy-2,4-dideoxy-2-fluoropentaric acid
Pentaric acid, 3-C-carboxy-2,4-dideoxy-2-fluoro-
1-Fluoro-2-hydroxypropane-1,2,3-tricarboxylic acid
安全数据
毒性A highly toxic material that kills by disrupting
energy metabolism. Specifically, fluorocitrate inhibits aconitase,
the enzyme responsible for conversion of citrate to isocitrate
in the citric acid (Krebs) cycle. It is likely that the
toxicities of fluoroacetamide and fluoroacetate can be attributed
to their conversion in vivo to fluorocitrate.