| Identification | Back Directory | [Name]
fluorocitrate | [CAS]
357-89-1 | [Synonyms]
fluorocitrate
Fluorocitric acid
2-Fluoro-L-erythro-citrate
Erythrofluorocitrate (isomer)
14466-42-3 (Unspecified hydrochloride salt)
3-C-Carboxy-2,4-dideoxy-2-fluoropentaric acid
Pentaric acid, 3-C-carboxy-2,4-dideoxy-2-fluoro- | [MOL File]
357-89-1.mol |
| Safety Data | Back Directory | [Toxicity]
A highly toxic material that kills by disrupting
energy metabolism. Specifically, fluorocitrate inhibits aconitase,
the enzyme responsible for conversion of citrate to isocitrate
in the citric acid (Krebs) cycle. It is likely that the
toxicities of fluoroacetamide and fluoroacetate can be attributed
to their conversion in vivo to fluorocitrate. |
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