382-44-5
382-44-5 结构式
基本信息
11Β-羟基雄甾-4-烯-3
4-雄甾烯-11-醇-3,17-二酮
4-雄烯-11β-醇-3,17-二酮
11β-羟基雄甾-4-烯-3,17-二酮
4-雄甾烯11Β-醇-3,17二酮-[D7]
11BETA-羟基-4-雄甾烯-3,17-二酮
4-雄甾烯-11Β-OL-3,17-二酮-2,2,4,6,6,16,16-D7
4-雄烯-11B-醇-3,17-二酮(2,2,4,6,6,16,16-D7,98%)
-dione
diol-d10
14&alpha
Decadiene
-9-
21-
20-
16-
15-
物理化学性质
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2025/02/08 | HY-114464 | 4-雄烯-11β-醇-3,17-二酮 11-Beta-hydroxyandrostenedione | 382-44-5 | 5mg | 400元 |
| 2025/02/08 | HY-114464 | 4-雄烯-11β-醇-3,17-二酮 11-Beta-hydroxyandrostenedione | 382-44-5 | 10mM * 1mLin DMSO | 440元 |
| 2025/02/08 | HY-114464 | 11β-羟基雄甾-4-烯-3,17-二酮 11-Beta-hydroxyandrostenedione | 382-44-5 | 10 mg | 640元 |
常见问题列表
|
Human Endogenous Metabolite
|
In order to establish that this conversion is catalysed by the lyase activity of CYP17A1, 21-deoxycortisol (21dF) and 21-deoxycortisone (21dE) is assayed within the LNCaP cell line. Upon the transfection of CYP17A1, 11-Beta-hydroxyandrostenedione (11OHA4)-pathway metabolites increase, 21dF and 21dE are in fact metabolised to 11-Beta-hydroxyandrostenedione and 11-ketoprogesterone (11KP4) by CYP17A1, respectively.
The plasma concentration of 11-Beta-hydroxyandrostenedione (11beta-hydroxy-4-androstene-3,17-dione) is very high in 21-hydroxylase deficiency, Cushing's syndrome, and hyperandrogenism of adrenal origin, and very low in congenital 11-hydroxylase deficiency and adrenal insufficiency. Thus, when plasma 4-androstenedione is elevated, it is useful to measure the plasma 11-Beta-hydroxyandrostenedione level in order to determine the adrenal or ovarian origin of the hyperandrogenism.