| Identification | Back Directory | [Name]
4-ANDROSTEN-11BETA-OL-3,17-DIONE | [CAS]
382-44-5 | [Synonyms]
u 2826
-dione
diol-d10
14&alpha
Decadiene
15-
16-
20-
21-
-9-
12H)
13a-
-14,
(9E,
11E)
9(11)
5(3H)
7(2H,
(13aS)
(17R)-4&rsquo
14(9H,
4-Androsten-11
Fluoro-
triene-
purine-
Benzo[a]
bis(oxy)
pyridine-
Dioxolan-
pyrrolo[1,
isoindole-
H)-furan]-3,3&rsquo
Oxime Estra-
dimethyl-1H-
4,6-trimethoxy-6'
isoquinoline-
methyl-pregna-
Anthraceneacetic Acid
norcrotalanan-
Benzisothiazol-
-ethyl-9-fluoro-11&beta
(8S,9S,10R,11S,13S,14S)
-[2]cyclohexene)-3,4'
(2S)-trans-7-Chloro-2'
[methylenebis(oxy)
HYDROCORTISONE IMPURITY 1
Hydrocortisone Impurity 3
methoxypentylidene)
4-Androsten-11β-ol-3,17-dione
4-androsten-11B-ol-3,17-dione
tetramethoxydibenzo[f,
11-BETA-HYDROXYANDROSTENEDIONE
4-Androsten-11-ol-3,17-dione-d7
Spiro[isobenzofuran-1(3H),1'
4-ANDROSTEN-11BETA-OL-3,17-DIONE
4-Androstene-11beta-ol-3,17-dione
11-Hydroxyandrost-4-ene-3,17-dione
11β-Hydroxy-4-Androsten-3,17-dione
-methylspiro(benzofuran-2[3H],1'
11β-Hydroxy-4-androstene-3,17-dione
11beta-Hydroxy-4-androsten-3,17-dione
11β-Hydroxy-androsta-4-ene-3,17-dione
-[1H,3H]naphtho[1,8-cd]pyran]-3,3'
4- androstene-3,17-dione -11β- alcohol
11BETA-HYDROXY-4-ANDROSTENE-3,17-DIONE
11 BETA-HYDROXYANDROST-4-ENE-3,17-DIONE
Androst-4-ene-3,17-dione, 11beta-hydroxy-
Taxilin, alpha (TXLNA) TXLN-alpha, IL
-methylspiro[androsta-1,4-diene-17,2&rsquo
(11beta)-11-Hydroxyandrost-4-ene-3,17-dione
Androst-4-ene-3,17-dione, 11-hydroxy-, (11beta)-
4-Androsten-11β-ol-3,17-dione-2,2,4,6,6,16,16-d7
Androst-4-ene-3,17-dione, 11-hydroxy-, (11beta)- (9CI)
-11-Hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)
(8S,9S,10R,11S,13S,14S)-11-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
(8S,9S,10R,11S,13S,14S)-11-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-quinone
(8S,9S,10R,11S,13S,14S)-11-hydroxy-10,13-diMethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione | [Molecular Formula]
C19H26O3 | [MDL Number]
MFCD00051131 | [MOL File]
382-44-5.mol | [Molecular Weight]
302.41 |
| Chemical Properties | Back Directory | [Melting point ]
197-199℃ | [Boiling point ]
475.3±45.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 250 mg/mL (826.69 mM) | [form ]
A crystalline solid | [pka]
14.49±0.60(Predicted) | [color ]
White to off-white | [InChI]
InChI=1S/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1 | [InChIKey]
WSCUHXPGYUMQEX-KCZNZURUSA-N | [SMILES]
C1[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]2(C)[C@@]3([H])CCC2=O)=CC(=O)C1 |
| Hazard Information | Back Directory | [Uses]
4-Androsten-11β-ol-3,17-dione is a steroid hormone. An analog of Androstenedione (A637550). | [Definition]
ChEBI: 11beta-hydroxyandrost-4-ene-3,17-dione is an 11beta-hydroxy steroid, a 3-oxo steroid, a 17-oxo steroid and an androstanoid. It has a role as a human metabolite and a mouse metabolite. | [Biochem/physiol Actions]
11β-Hydroxy-4-androstene-3,17-dione is a naturally occurring steroid that is primarily, if not strictly, produced in adrenal tissue. In diseases such as Cushing′s syndrome, adrenal-originated hyperandrogenism, and congenital adrenal hyperplasia, plasma 11β levels are very high. Plasma 11β concentration is very low in congenital 11-hydroxylase deficiency and adrenal insufficiency. | [in vivo]
The plasma concentration of 11-Beta-hydroxyandrostenedione (11beta-hydroxy-4-androstene-3,17-dione) is very high in 21-hydroxylase deficiency, Cushing's syndrome, and hyperandrogenism of adrenal origin, and very low in congenital 11-hydroxylase deficiency and adrenal insufficiency. Thus, when plasma 4-androstenedione is elevated, it is useful to measure the plasma 11-Beta-hydroxyandrostenedione level in order to determine the adrenal or ovarian origin of the hyperandrogenism[1]. | [IC 50]
Human Endogenous Metabolite |
|
| Company Name: |
Sigma-Aldrich
|
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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