55-43-6
中文名称
N-(2-氯乙基)二苄胺盐酸盐
英文名称
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
CAS
55-43-6
EINECS 编号
200-234-5
分子式
C16H19Cl2N
MDL 编号
MFCD00012518
分子量
296.23
MOL 文件
55-43-6.mol
更新日期
2024/04/23 11:12:52
55-43-6 结构式
基本信息
中文别名
N-(2-氯乙基)二苄胺盐酸盐二苄氨基氯乙烷盐酸盐
盐酸二苄乃明
N,N-联苄基-2-氯乙胺盐酸盐
英文别名
DIBENAMINE HYDROCHLORIDEN-(2-CHLOROETHYL)DIBENZYLAMINE HCL
N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
N,N'-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE
N,N-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE
N,N-DIBENZYLAMINOETHYLCHLORIDE HYDROCHLORIDE
N,N-DIBENZYL-BETA-CHLOROETHYLAMINE HYDROCHLORIDE
dibenzylchlorethylaminehydrochloride
n-(2-chloroethyl)-dibenzylaminhydrochloride
n-(2-chloroethyl)-n-(phenylmethyl)-benzenemethanaminhydrochloride
dibenzyl(2-chloroethyl)ammonium chloride
n,n-dibenzyl-2-chloroethylamineHCl
DIBENZYLAMINE,N-(2-CHLOROETHYL)-,HYDROCHLORIDE
N-(2-Chloroethyl)-N-(phenylmethyl)benzmetanamine chlorohydrate
Sympatholytin hydrochloride
所属类别
有机原料：无环单胺、多胺及其衍生物和盐物理化学性质
熔点190-193 °C(lit.)
沸点449.72°C (rough estimate)
密度1.1507 (rough estimate)
折射率1.6300 (estimate)
储存条件Inert atmosphere,Room Temperature
溶解度在甲醇中几乎透明
形态结晶粉末
颜色白色至灰白色
Merck2138
安全数据
警示词警告
危险性描述H315-H319-H335
危险品标志Xi
危险类别码R36/37/38
安全说明S26-S37/39
WGK Germany3
RTECS号HQ6825000
危险等级IRRITANT
海关编码29214900
毒性LD50 s.c. in mice: 800 mg/kg (Nickerson, Nomaguchi)
N-(2-氯乙基)二苄胺盐酸盐价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-128380 | N-(2-氯乙基)二苄胺盐酸盐 Dibenamine hydrochloride | 55-43-6 | 250mg | 500元 |
| 2024/01/25 | HY-128380 | N-(2-氯乙基)二苄胺盐酸盐 Dibenamine hydrochloride | 55-43-6 | 10mM * 1mLin DMSO | 550元 |
| 2024/01/16 | S5432 | N-(2-氯乙基)二苄胺盐酸盐 Dibenamine Hydrochloride | 55-43-6 | 25mg | 794.48元 |
常见问题列表
生物活性
Dibenamine hydrochloride 是一种竞争和不可逆的肾上腺素能 (b>adrenergic) 阻断剂，可以修饰肾上腺素的药理作用。Dibenamine hydrochloride 对小鼠体内肾上腺素的破坏率显著增加。靶点
IC50: Adrenergic receptor
体外研究
Dibenamine (100 nM-10 μM) attenuates the degree of cocaine-induced increase in sensitivity to acetylcholine without any effect on acetylcholine-contraction in isolated vas deferens of guinea pig. Additionally, the degree of dibenamine-induced inhibition dependent on the concentration of dibenamine and inversely related to the concentration of cocaine.
体内研究
Dibenamine hydrochloride (subcutaneous injection; 25 mg/kg; 48 and 24 hr before the administration of CCl4) decreases the CHCl3, levels at 2 and 6 hr by 30-50 percent, but did not appreciably affect the half-life of CHCl3, in the liver.Pretreatment with Dibenamine apparently slows the conversion of Ccl4 to CHCL3.