61345-83-3
中文名称
N1,N12-二乙酰精胺
英文名称
N1,N12-Diacetylspermine
CAS
61345-83-3
分子式
C14H30N4O2
分子量
286.41
MOL 文件
61345-83-3.mol
61345-83-3 结构式
基本信息
中文别名
N1,N12-二乙酰精胺 英文别名
N1,N12-DiacetylspermineN,N'-Bis(3-acetylaminopropyl)-1,4-butanediamine
N-[3-[4-(3-acetamidopropylamino)butylamino]propyl]acetamide
Acetamide, N,N'-[1,4-butanediylbis(imino-3,1-propanediyl)]bis-
物理化学性质
储存条件2-8°C
形态solid
主要应用clinical testing
InChI1S/C14H30N4O2/c1-13(19)17-11-5-9-15-7-3-4-8-16-10-6-12-18-14(2)20/h15-16H,3-12H2,1-2H3,(H,17,19)(H,18,20)
InChIKeyNPDTUDWGJMBVEP-UHFFFAOYSA-N
SMILESN(CCCNC(=O)C)CCCCNCCCNC(=O)C
应用领域
用途一
N1,N12-Acetylspermine is a diacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. Upregulation of N1,N12-acetylspermine has been linked to the incidence of cancer, making this natural polyamine a potential biomarker for cancer detection.[Cayman Chemical]