6452-73-9
中文名称
盐酸氧烯洛尔
英文名称
OXPRENOLOL HYDROCHLORIDE
CAS
6452-73-9
EINECS 编号
229-260-5
分子式
C15H24ClNO3
MDL 编号
MFCD00058008
分子量
301.81
MOL 文件
6452-73-9.mol
更新日期
2024/04/14 10:33:41
6452-73-9 结构式
基本信息
中文别名
盐酸氧烯洛尔 英文别名
1-[2-(ALLYLOXY)PHENOXY]-3-[ISOPROPYLAMINO]-2-PROPANOL HYDROCHLORIDELABOTEST-BB LT00772178
OXPRENOLOL HYDROCHLORIDE
1-(o-allyloxyphenoxy)-3-isopropylamino-2-propanohydrochloride
1-(o-allyloxyphenoxy)-3-isopropylaminopropan-2-olhydrochloride
2-(o-allyloxyphenoxy)-2-hydroxy-n-isopropyl-1-propylaminehydrochloride
ba-39089
c-39089-ba
ciba39089ba
1-[2-ALLYLOXYPHENOXY]-3-[ISOPROPYLAMINO]-2-PROPANOLHCl
2-Propanol, 1-(1-methylethyl)amino-3-2-(2-propenyloxy)phenoxy-, hydrochloride
(+-)-1-[o-(Allyloxy)phenoxy]-3-isopropylamino-2-propanol hydrochloride
1-(2'-Allyloxyphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride
1-(2-Allyloxyphenoxy)-2-hydroxy-3-isopropylaminopropane hydrochloride
1-(o-Allyloxyphenoxy)-3-isopropylamino-2-propanol hydrochloride
1-(o-Allyloxyphenoxy)-3-isopropylamino-2-propranol-hydrochloride
1-Isopropyl-amino-2-hydroxy-3-(O-allyloxyphenoxy)propane hydrochloride
1-Isopropylamino-3-(o-allyloxyphenoxy)-2-propanol hydrochloride
2-Propanol, 1-[(1-methylethyl)amino]-3-[2-(2-propenyloxy)phenoxy]-, hydrochloride (9CI)
2-Propanol, 1-[o-(allyloxy)phenoxy]-3-(isopropylamino)-, hydrochloride (7CI, 8CI)
所属类别
原料药：抗心律失常药安全数据
6452-73-9(安全特性,毒性,储运)
储运特性
库房通风低温干燥; 与食品原料分开存放毒性分级
中毒急性毒性
口服-大鼠LD50: 900 毫克/公斤可燃性危险特性
可燃;燃烧产生有毒氮氧化物和氯化氢烟雾类别
有毒物品灭火剂
干粉、泡沫、砂土、二氧化碳, 雾状水常见问题列表
生物活性
Oxprenolol hydrochloride (Ba 39089) 是一种口服有效的 β-肾上腺素受体 (β-AR) 拮抗剂，Ki 为 7.10 nM。靶点
Ki: 7.10 nM (β-adrenergic receptor)
体内研究
Oxprenolol (200 mg/kg/day; administered orally; for 3 weeks) produces effective beta-blockade.
| Animal Model: | Male rats (230 to 300 g body wt) of the Wistar strain |
| Dosage: | 200 mg/kg |
| Administration: | Administered orally; daily for 3 weeks |
| Result: | This dosage produced effective beta-blockade. |