68399-76-8
中文名称
乳清酸锌二水合物
英文名称
OROTIC ACID ZINC SALT DIHYDRATE
CAS
68399-76-8
分子式
C10H10N4O10Zn
分子量
411.6
MOL 文件
68399-76-8.mol
68399-76-8 结构式
基本信息
中文别名
乳清酸锌二水合物乳清酸 锌盐 二水合物
乳清酸锌二水合物|乳清酸锌
英文别名
ZINC OROTATEZincorotate2H2O
Orotic acid zinc
Orotic acid zinc saL
Zn Orotate USP/EP/BP
OROTIC ACID ZINC SALT DIHYDRATE
Orotic acid dihydrate zinc salt
Orotic acid zinc salt dihydrate >=98.0%
zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate
zinc 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate (1:2)
所属类别
食品添加剂常见问题列表
生物活性
Orotic acid (zinc)，一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。Orotic acid (zinc) 是尿素循环异常的常规新生儿筛查中的测量指标。Orotic acid (zinc) 可引起大鼠肝脂肪变性和肝肿大。体外研究
Orotic acid is found in milk and dairy products, and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver, kidney and erythrocytes.
体内研究
Orotic acid is a marker for measurement of urea cycle disorders (UCDs), including ornithine transcarbamylase deficiency (OTCD).
Orotic acid (1.0% addition to the diet; p.o. for 3-10 d) induces a development of fatty liver by day 7, and decreases purine/pyrimidine ratio of hepatic acid-soluble nucleotides by day 3.