78263-91-9
中文名称
2-METHYLSEROTONIN MALEATE SALT
英文名称
2-METHYLSEROTONIN MALEATE SALT
CAS
78263-91-9
分子式
C15H18N2O5
分子量
306.314
MOL 文件
78263-91-9.mol
78263-91-9 结构式
基本信息
中文别名
化合物 T10075L 英文别名
2-Me-HT maleate2-Me-5-HT maleate
2-Methyl-5-HT maleate
2-METHYLSEROTONIN MALEATE SALT
2-methyl-5-hydroxytryptamine maleate salt
3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol maleate salt
2-Methyl-5-hydroxytryptamine maleate salt, 3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol maleate salt
物理化学性质
熔点186-187 °C
储存条件−20°C
溶解度H2O：可溶5mg/mL，澄清
形态粉末
颜色白色至棕色
水溶解性H2O: 5mg/mL, clear
InChI1S/C11H14N2O.C4H4O4/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7;5-3(6)1-2-4(7)8/h2-3,6,13-14H,4-5,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKeyKFEAUMZKRNJEDU-BTJKTKAUSA-N
SMILESOC1=CC2=C(NC(C)=C2CCN)C=C1.OC(/C=C\C(O)=O)=O
常见问题列表
生物活性
2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) 是一种有效的选择性 5-HT3 受体激动剂。2-Methyl-5-HT maleate 显示出抗抑郁样作用。靶点
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5-HT 3 Receptor
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体内研究
2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) (i.p.; 3 mg/kg; 45 minutes) significantly decreases time of immobility as compared to controls thus showing anti-depressive-like effects.
| Animal Model: | Male Sprague-Dawley rats |
| Dosage: | 3 mg/kg |
| Administration: | I.p.; 45 minutes |
| Result: | Significantly decreased time of immobility thus showing anti-depressive-like effects. |