| Identification | Back Directory | [Name]
2-METHYLSEROTONIN MALEATE SALT | [CAS]
78263-91-9 | [Synonyms]
2-Me-HT maleate
2-Me-5-HT maleate
2-Methyl-5-HT maleate
2-METHYLSEROTONIN MALEATE SALT
2-methyl-5-hydroxytryptamine maleate salt
3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol maleate salt
2-Methyl-5-hydroxytryptamine maleate salt, 3-(2-Aminoethyl)-2-methyl-1H-indol-5-ol maleate salt | [Molecular Formula]
C15H18N2O5 | [MDL Number]
MFCD00082467 | [MOL File]
78263-91-9.mol | [Molecular Weight]
306.314 |
| Chemical Properties | Back Directory | [Melting point ]
186-187 °C | [storage temp. ]
−20°C | [solubility ]
H2O: soluble5mg/mL, clear | [form ]
powder | [color ]
white to brown | [Water Solubility ]
H2O: 5mg/mL, clear | [InChI]
1S/C11H14N2O.C4H4O4/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7;5-3(6)1-2-4(7)8/h2-3,6,13-14H,4-5,12H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1- | [InChIKey]
KFEAUMZKRNJEDU-BTJKTKAUSA-N | [SMILES]
OC1=CC2=C(NC(C)=C2CCN)C=C1.OC(/C=C\C(O)=O)=O |
| Hazard Information | Back Directory | [Uses]
2-Methylserotonin Maleate Salt is a 5-HT3 serotonin receptor agonist. | [Biological Activity]
2-Methylserotonin is a selective full agonist at the 5-HT3 receptor.''2-Methylserotonin maleatea serotonin type 3 (5-HT3) agonist is used as a training drug in drug discrimination studies. Use of 2-methylserotonin in evolving rats shows to reflect the ontogeny of the spinal 5-HT3 receptor system. | [in vivo]
2-Methyl-5-HT maleate (2-Methyl-5-hydroxytryptamine maleate) (i.p.; 3 mg/kg; 45 minutes) significantly decreases time of immobility as compared to controls thus showing anti-depressive-like effects[1]. | Animal Model: | Male Sprague-Dawley rats[1] | | Dosage: | 3 mg/kg | | Administration: | I.p.; 45 minutes | | Result: | Significantly decreased time of immobility thus showing anti-depressive-like effects.
|
| [IC 50]
5-HT3 Receptor |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
|