83136-88-3
中文名称
CYCLOPIAZONIC ACID
英文名称
CYCLOPIAZONIC ACID
CAS
83136-88-3
分子式
C20H20N2O3
分子量
336.38
MOL 文件
83136-88-3.mol
83136-88-3 结构式
基本信息
英文别名
CPACYCLOPIAZONIC ACID
PENICILLIUM CYCLOPIUM
ALPHA CYCLOPIAZONIC ACID
CYCLOPIAZONIC ACID, PENICILLIUM CYCLOPIUM
(6AR,11AS,11BR)-REL-10-ACETYL-2,6,6A,7,11A,11B-HEXAHYDRO-7,7-DIMETHYL-9H-PYRROLO[1',2':2,3]ISOINDOLO[4,5,6-CD]INDOL-9-ONE
6H-Pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indole-9,11(2H,7H)-dione, 6a,10,11a,11b-tetrahydro-10-(1-hydroxyethylidene)-7,7-dimethyl-, (6aR,10Z,11aS,11bR)-
(6AA, 10Z, 11AB, 11BA)-6A,7,11A,11B-TETRAHYDRO-10-(1-HYDROXYETHYLIDENE)-7,7- DIMETHYL-6H-PYRROLO [1',2':2,3]ISOINDOLO [4,5,6-CD]INDOLE-9,11 (2H,10H)-DIONE
所属类别
生物：PCR试剂安全数据
危险品标志T
危险类别码25
安全说明36/37/39-45
危险品运输编号UN 2811 6.1/PG 2
WGK Germany3
RTECS号UY8587000
毒性Cyclopiazonic acid is a natural contaminant of
cheese, corn, and peanuts. Due to the lack of analytical methods
for quantifying cyclopiazonic acid, the amount present in
the food supply and the potential health risks are uncertain.
Cyclopiazonic acid distributes widely in mammalian tissues,
especially skeletal muscle, and produces equally diverse cytotoxicity.
This toxicant shares many pharmacological properties
with antipsychotic drugs including catalepsy, hypothermia,
hypokinesia, ptosis, tremor, gait disturbance, sedation without
loss of righting reflex, atypical convulsion, and increased barbiturate
sleeping time. The mode of action of cyclopiazonic
acid involves its role as an inhibitor of Ca-ATPase.