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864082-48-4

中文名称 化合物 T27479
英文名称 GSK466317A
CAS 864082-48-4
分子式 C21H16ClF3N4O2
分子量 448.83
MOL 文件 864082-48-4.mol
864082-48-4 结构式 864082-48-4 结构式

基本信息

中文别名
化合物 T27479
英文别名
GSK466317A

物理化学性质

沸点713.4±60.0 °C(Predicted)
密度1.485±0.06 g/cm3(Predicted)
酸度系数(pKa)11.54±0.40(Predicted)

应用领域

用途一
GSK466317A is a GRK2 inhibitor. GRK2 has been directly implicated in the progression of heart failure. Selective inhibitors of individual subfamilies of G protein-coupled receptor kinases (GRKs) would serve as useful chemical probes as well as leads for therapeutic applications ranging from heart failure to Parkinson's disease.
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