955900-27-3
中文名称
化合物 T28543
英文名称
1-[(E)-[4-methoxy-3-[(4-nitropyrazol-1-yl)methyl]phenyl]methylideneamino]-3-prop-2-enylthiourea
CAS
955900-27-3
分子式
C16H18N6O3S
分子量
374.42
MOL 文件
955900-27-3.mol
955900-27-3 结构式
基本信息
中文别名
化合物 T28543 英文别名
RK9123016RK 9123016
RK-9123016
1-[(E)-[4-methoxy-3-[(4-nitropyrazol-1-yl)methyl]phenyl]methylideneamino]-3-prop-2-enylthiourea
Hydrazinecarbothioamide, 2-[[4-methoxy-3-[(4-nitro-1H-pyrazol-1-yl)methyl]phenyl]methylene]-N-2-propen-1-yl-
应用领域
用途一
RK-9123016 is a small molecule inhibitor of SIRT2. The compound increases the acetylation level of eukaryotic translation initiation factor 5A (eIF5A), a physiological substrate of SIRT2, and reduces cell viability of human breast cancer cells accompanied with a decrease in c-Myc expression.