992-20-1
992-20-1 结构式
基本信息
中文别名
化合物 T34488 英文别名
SALANNIN(P)Azadriactin
Caswell no. 594a
Azadirachtin, neem
Margosan-o-concentrate
2H,3H-Cyclopenta(D')naphtho(1,8-bc:2,3-B')difuran-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2A,4,5,5A,6,6A,8,9,9A,10A,10B,10C-dodecahydro-2A,5A,6A,7-tetramethyl-5-(((2E)-2-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (2ar,3R,5S,5ar,6R,6ar,8R,9ar,10as,10br,10cr)-
2H,3H-Cyclopenta(D')naphtho(1,8-bc:2,3-B')difuran-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2A,4,5,5A,6,6A,8,9,9A,10A,10B,10C-dodecahydro-2A,5A,6A,7-tetramethyl-5-((2-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (2aalpha,3beta,5beta(E), 5aalpha,6alpha,6aalpha,8beta,9abeta,10aalpha,10balpha,10cbeta)-(+)-
物理化学性质
熔点167～170℃
沸点631.9±55.0 °C(Predicted)
密度1.24±0.1 g/cm3(Predicted)
储存条件-20°C储存
溶解度可溶于氯仿（少许）、甲醇（少许）
形态固体
颜色白色至灰白色
LogP5.560 (est)
EPA化学物质信息Salannin (992-20-1)
常见问题列表
生物活性
Salannin，一种柠檬苦素，具有抗溃疡和杀精活性。Salannin 对革兰氏阳性菌和革兰氏阴性菌均有抗菌活性。体内研究
Salannin (10, 20, 50 mg/kg; p.o.) shows a significant protective activity on Aspirin (HY-14654) induced gastric lesions.
| Animal Model: | Wistar rats, weighing 200-220 g (acetyl salicylic acid induced gastric lesions) |
| Dosage: | 10, 20 and 50 mg/kg |
| Administration: | P.o. |
| Result: | Significantly and dose dependently inhibited acetyl salicylic acid-induced gastric lesions. |