992-20-1

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992-20-1 Structure

Identification	Back Directory
[Name] SALANNIN(P)
[CAS] 992-20-1
[Synonyms] SALANNIN(P) Azadriactin Caswell no. 594a Azadirachtin, neem Margosan-o-concentrate 2H,3H-Cyclopenta(D')naphtho(1,8-bc:2,3-B')difuran-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2A,4,5,5A,6,6A,8,9,9A,10A,10B,10C-dodecahydro-2A,5A,6A,7-tetramethyl-5-(((2E)-2-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (2ar,3R,5S,5ar,6R,6ar,8R,9ar,10as,10br,10cr)- 2H,3H-Cyclopenta(D')naphtho(1,8-bc:2,3-B')difuran-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2A,4,5,5A,6,6A,8,9,9A,10A,10B,10C-dodecahydro-2A,5A,6A,7-tetramethyl-5-((2-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (2aalpha,3beta,5beta(E), 5aalpha,6alpha,6aalpha,8beta,9abeta,10aalpha,10balpha,10cbeta)-(+)-
[Molecular Formula] C34H44O9
[MDL Number] MFCD00210552
[MOL File] 992-20-1.mol
[Molecular Weight] 596.71

Chemical Properties	Back Directory
[Melting point ] 167～170℃
[Boiling point ] 631.9±55.0 °C(Predicted)
[density ] 1.24±0.1 g/cm3(Predicted)
[storage temp. ] Store at -20°C
[solubility ] Chloroform (Slightly), Methanol (Slightly)
[form ] Solid
[color ] White to Off-White
[LogP] 5.560 (est)
[EPA Substance Registry System] Salannin (992-20-1)

[Uses]

Salannin is a limonoid found in Neem with a possible melanogenesis-inhibitory activity.

[Definition]

ChEBI: A limonoid with insecticidal activity isolated from Azadirachta indica.

[in vivo]

Salannin (10, 20, 50 mg/kg; p.o.) shows a significant protective activity on Aspirin (HY-14654) induced gastric lesions^[2].

Animal Model:	Wistar rats, weighing 200-220 g (acetyl salicylic acid induced gastric lesions)^[2]
Dosage:	10, 20 and 50 mg/kg
Administration:	P.o.
Result:	Significantly and dose dependently inhibited acetyl salicylic acid-induced gastric lesions.

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2495-25-2 688-84-6 101-43-9 142-90-5

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