| Identification | Back Directory | [Name]
SALANNIN(P) | [CAS]
992-20-1 | [Synonyms]
SALANNIN(P)
Azadriactin
Caswell no. 594a
Azadirachtin, neem
Margosan-o-concentrate
2H,3H-Cyclopenta(D')naphtho(1,8-bc:2,3-B')difuran-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2A,4,5,5A,6,6A,8,9,9A,10A,10B,10C-dodecahydro-2A,5A,6A,7-tetramethyl-5-(((2E)-2-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (2ar,3R,5S,5ar,6R,6ar,8R,9ar,10as,10br,10cr)-
2H,3H-Cyclopenta(D')naphtho(1,8-bc:2,3-B')difuran-6-acetic acid, 3-(acetyloxy)-8-(3-furanyl)-2A,4,5,5A,6,6A,8,9,9A,10A,10B,10C-dodecahydro-2A,5A,6A,7-tetramethyl-5-((2-methyl-1-oxo-2-butenyl)oxy)-, methyl ester, (2aalpha,3beta,5beta(E), 5aalpha,6alpha,6aalpha,8beta,9abeta,10aalpha,10balpha,10cbeta)-(+)- | [Molecular Formula]
C34H44O9 | [MDL Number]
MFCD00210552 | [MOL File]
992-20-1.mol | [Molecular Weight]
596.71 |
| Chemical Properties | Back Directory | [Melting point ]
167～170℃ | [Boiling point ]
631.9±55.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [LogP]
5.560 (est) | [EPA Substance Registry System]
Salannin (992-20-1) |
| Hazard Information | Back Directory | [Uses]
Salannin is a limonoid found in Neem with a possible melanogenesis-inhibitory activity. | [Definition]
ChEBI: A limonoid with insecticidal activity isolated from Azadirachta indica. | [in vivo]
Salannin (10, 20, 50 mg/kg; p.o.) shows a significant protective activity on Aspirin (HY-14654) induced gastric lesions[2]. | Animal Model: | Wistar rats, weighing 200-220 g (acetyl salicylic acid induced gastric lesions)[2] | | Dosage: | 10, 20 and 50 mg/kg | | Administration: | P.o. | | Result: | Significantly and dose dependently inhibited acetyl salicylic acid-induced gastric lesions.
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