EXO 1
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- CAS号:
- 75541-83-2
- 英文名:
- EXO1
- 英文别名:
- EXO1;EOX 1;NSC 214045;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-Fluoro-benzoylami;Exo 1 >=98% (HPLC), solid;Exo1 - CAS 75541-83-2 - Calbiochem;Exo1,inhibit,Exo-1,Exo 1,Inhibitor;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
- 中文名:
- EXO 1
- 中文别名:
- 化合物EXO1;2- [(4-氟苯甲酰基)氨基]苯甲酸甲酯
- CBNumber:
- CB0713355
- 分子式:
- C15H12FNO3
- 分子量:
- 273.26
- MOL File:
- 75541-83-2.mol
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EXO 1化学性质
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储存条件:
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+2C to +8C
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溶解度:
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DMSO: 19 mg/mL, soluble
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形态:
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solid
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EXO 1性质、用途与生产工艺
Exo1 (2-(4-Fluorobenzoylamino)-benzoic acid methyl ester)是一种针对 exocytosis 的可逆抑制剂，可诱导 Golgi 迅速塌陷至内质网和来自高尔基体的 ADP-ribosylation factor (ARF) 1 的快速释放。
| Target | Value |
exocytosis
()
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Golgi
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ARF-1
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Exo1 is a modifier of Golgi ARF1 GTPase activity. Because Exo1 affects a subset of the membrane events that are blocked by BFA, but seems to have a different protein target (and presumably has different side effects), it provides an independent means to interfere with Golgi activity. Exo1 Disrupts Vesicular Traffic from the ER to the Golgi apparatus by disrupting Golgi structures. Exo1 inhibits exocytosis with an IC
50
of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I.
EXO 1
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | S6800 | EXO 1
Exo1 | 75541-83-2 | 5mg | 390.25元 |
| 2023/03/20 | S6800 | EXO 1
Exo1 | 75541-83-2 | 25mg | 1265.48元 |
EXO 1
生产厂家
全球有 46家供应商
EXO 1国内生产厂家
75541-83-2, EXO 1 相关搜索:
- 药靶配体
- C15H12NFO3
- 化合物EXO1
- 2- [(4-氟苯甲酰基)氨基]苯甲酸甲酯
- 75541-83-2
- Exo1,inhibit,Exo-1,Exo 1,Inhibitor
- Exo 1 >=98% (HPLC), solid
- Benzoic acid, 2-[(4-fluorobenzoyl)amino]-, methyl ester
- Exo1 - CAS 75541-83-2 - Calbiochem
- NSC 214045
- EXOCYTIC INHIBITOR 1;NSC 214045;EXO 1;EXO-1
- Exo1, Exocytic Inhibitor 1, 2-(4-Fluoro-benzoylaMino)-benzoic acid Methyl ester
- EXO1
- EXOCYTIC INHIBITOR 1
- EOX 1
- 2-(4-Fluorobenzoylamino)benzoic acid methyl ester, 2-(4-Fluorobenzoylamino)methylbenzoate
- 2-(4-Fluoro-benzoylami
- 2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
- 2-(4-FLUOROBENZOYLAMINO)BENZOIC ACID METHYL ESTER
- 4-FLUORO-BZ-2-ABZ-OME