EXO1
- CAS No.
- 75541-83-2
- Chemical Name:
- EXO1
- Synonyms
- EXO1;EOX 1;NSC 214045;EXOCYTIC INHIBITOR 1;4-FLUORO-BZ-2-ABZ-OME;2-(4-Fluoro-benzoylami;Exo 1 >=98% (HPLC), solid;Exo1 - CAS 75541-83-2 - Calbiochem;Exo1,inhibit,Exo-1,Exo 1,Inhibitor;2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
- CBNumber:
- CB0713355
- Molecular Formula:
- C15H12FNO3
- Molecular Weight:
- 273.26
- MDL Number:
- MFCD00028104
- MOL File:
- 75541-83-2.mol
EXO1 price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | E8280 | Exo 1 ≥98% (HPLC), solid | 75541-83-2 | 5mg | $69.3 | 2024-03-01 | Buy |
| Sigma-Aldrich | 341220 | Exo1 | 75541-83-2 | 25mg | $182 | 2024-03-01 | Buy |
| Cayman Chemical | 18455 | Exo 1 ≥99% | 75541-83-2 | 10mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 18455 | Exo 1 ≥99% | 75541-83-2 | 50mg | $324 | 2024-03-01 | Buy |
| Sigma-Aldrich | E8280 | Exo 1 ≥98% (HPLC), solid | 75541-83-2 | 25mg | $244 | 2024-03-01 | Buy |
EXO1 Chemical Properties,Uses,Production
Uses
Exo 1 acts as a cell-permeable reverse inhibitor of exocytosis. Potential anti-inflammatory activity.
Uses
Exo 1 has been used as a component of the BRB80 buffer to study coat protein 1 (COPI)-mediated membrane trafficking. It has also been used as a Golgi inhibitor to study its effects on the long?interspersed?nuclear?element-1 (L1) retrotransposition.
Uses
Exo1 is a cell-permeable, reversible inhibitor of exocytosis (IC50 = 20 μM). It interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum by dissociating the GTPase activator ADP-ribosylation factor (ARF1) from Golgi membranes, which leads to a consequent collapse of the Golgi apparatus.
Definition
ChEBI: 2-[[(4-fluorophenyl)-oxomethyl]amino]benzoic acid methyl ester is a member of benzamides.
Biochem/physiol Actions
Exo 1 is a cell-permeable methylanthranilate analog that promotes the release of adenosine diphosphate (ADP)-ribosylation factor (ARF) 1 from Golgi membranes. It also inhibits the membrane trafficking between the endoplasmic reticulum (ER) and the Golgi bodies.
EXO1 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15421 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 27322 | 60 |