OSAJIN
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- CAS号:
- 482-53-1
- 英文名:
- OSAJIN
- 英文别名:
- OSAJIN;CID 95168;NSC 21565;OSAJIN(RG);Osajin >=95% (LC/MS-ELSD);5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one;5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-pyrano[2,3-f]chromen-4-one;5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one;4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one,5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-
- 中文名:
- OSAJIN
- 中文别名:
- 奥沙京
- CBNumber:
- CB0762777
- 分子式:
- C25H24O5
- 分子量:
- 404.46
- MOL File:
- 482-53-1.mol
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OSAJIN化学性质
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熔点:
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189° (uncorr), 193° (corr)
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沸点:
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632.3±55.0 °C(Predicted)
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密度:
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1.258±0.06 g/cm3(Predicted)
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储存条件:
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-20°C
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溶解度:
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Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
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形态:
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powder
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酸度系数(pKa):
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7.00±0.40(Predicted)
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颜色:
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Yellow
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OSAJIN性质、用途与生产工艺
Osajin是 Maclura pomifera 果实中存在的主要生物活性异黄酮，具有抗肿瘤，抗氧化和抗炎活性。
Osajin significantly decreases the viability of human NPC cells (TW076, CG1 and TW04 cells) in a dose-dependent manner. Osajin induces apoptosis in human NPC cells through multiple apoptotic pathways, including the extrinsic death receptor pathway, and intrinsic pathways relying on mitochondria and endoplasmic reticulum stress. Osajin exhibits growth inhibitory activity on six human cancer cell lines, including kidney, lung, prostate, breast, melanoma and colon cancer cells.
Osajin and pomiferin attenuates the myocardial dysfunction provoked by ischemia reperfusion. This is confirmed by an increase in both antioxidant enzyme values and total antioxidant activity. The cardioprotection provided by osajin and pomiferin treatment results from the suppression of oxidative stress and this correlates with improved ventricular function.
OSAJIN
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/01/25 | HY-N3125 | Osajin | | 1 mg | 3100元 |
482-53-1, OSAJIN 相关搜索:
- 黄酮
- 标准品 -对照药材
- 植物提取物
- 标准品
- C25H24O5
- 奥沙京
- 482-53-1
- Osajin >=95% (LC/MS-ELSD)
- CID 95168
- NSC 21565
- 4H,8H-Benzo[1,2-b:3,4-b']dipyran-4-one,5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-buten-1-yl)-
- 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-pyrano[2,3-f]chromen-4-one
- OSAJIN(RG)
- 5-hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one
- 5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6-(3-methyl-2-butenyl)-4H,8H-benzo[1,2-b:3,4-b']dipyran-4-one
- OSAJIN