(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
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- CAS号:
- 4272-74-6
- 英文名:
- TLCK
- 英文别名:
- TLCK;TLCK HCL;(s)-lorid;TOS-LYS-CMK;TOSYL-LYS-CMK;TLCK USP/EP/BP;TOS-LYS-CMK HCL;Tos-L-Lys-CMK·HCl;TLCK HYDROCHLORIDE;Tos-Lys-chloromethylketone
- 中文名:
- (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
- 中文别名:
- TLCK(进分);化合物 T16169;NA-对甲苯磺酰-L-赖氨酸氯甲基酮盐酸盐;NΑ-甲苯磺胺基-L-赖氨酸氯甲基酮盐酸盐;NΑ-甲苯磺酰基-L-赖氨酸氯甲基酮盐酸盐;NALPHA-甲苯磺胺基-L-赖氨酸氯甲基酮盐酸盐;(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐;(3S)-1-氯-3-甲苯磺酰基氨-7-氨基-2-庚酮盐酸盐;NΑ-甲苯磺酰基- L -赖氨酸氯甲基酮 盐酸盐;化合物N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
- CBNumber:
- CB1197729
- 分子式:
- C14H21ClN2O3S.ClH
- 分子量:
- 369.31
- MOL File:
- 4272-74-6.mol
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(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐化学性质
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熔点:
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~165 °C (dec.)
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储存条件:
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-20°C
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溶解度:
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H2O: 50 mg/mL
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形态:
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powder
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颜色:
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white to pink
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旋光性 (optical activity):
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[α]20/D 7.8±0.5°, c = 2% in H2O
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BRN:
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7106867
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CAS 数据库:
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4272-74-6
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(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐性质、用途与生产工艺
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK) 是一种胰蛋白酶样蛋白酶抑制剂,使 HeLa 细胞对 Fas 介导的细胞死亡敏感。
N-alpha-Tosyl-L-lysine chloromethyl ketone exhibits an inhibitory effect on IFN-γ activities. The effect of TLCK is studied on the IFN-γ sensitization of HeLa cells towards cell death mediated by anti-Fas. Lower concentration of anti-Fas (10 ng/mL) are used to examine the interaction among the three effectors simultaneously, that is, anti-Fas, TLCK and IFN-γ. TLCK by itself up to 50 μM concentration exhibits a small decrease in cell viability. Beyond 50 μM, a dose dependent decrease in cell viability is observed. IFN-γ slightly reduces cell viability on its own. Addition of anti-Fas (10 ng/mL) results in a slight decrease in cell survival, which is enhanced more than additively in the presence of TLCK, most prominently between 50 and 100 μM. Upon addition of both anti-Fas and IFN-γ, a decrease (≈46%) in cell viability is observed. Moreover, the decrease in cell survival is further enhanced upon addition of higher concentrations of TLCK, 25 μM and more.
(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
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更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | 22795 | (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐 (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, 98%, Thermo Scientific Chemicals | 4272-74-6 | 50mg | 804元 |
2024/08/19 | 22795 | (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐 (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, 98%, Thermo Scientific Chemicals | 4272-74-6 | 250mg | 3257元 |
(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
生产厂家
4272-74-6, (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐 相关搜索:
- inhibitor
- 高端化学
- 通用生化试剂-氨基酸
- 生化试剂-氨基酸类
- 蛋白酶抑制剂
- 氨基酸类
- 氨基酸
- 细胞裂解蛋白酶抑制剂
- Trypsin Inhibitors
- Enzyme Inhibitors by Type
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors
- Analytical Enzymes
- Biochemicals and Reagents
- BioChemical
- Organic Covalent Modifiers
- C14H22N2O3Scl
- C14H21ClN2O3S
- C14H21ClN2O3SHCl
- NΑ-甲苯磺酰基- L -赖氨酸氯甲基酮 盐酸盐
- 化合物N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
- 化合物 T16169
- NΑ-甲苯磺酰基-L-赖氨酸氯甲基酮盐酸盐
- NALPHA-甲苯磺胺基-L-赖氨酸氯甲基酮盐酸盐
- (3S)-1-氯-3-甲苯磺酰基氨-7-氨基-2-庚酮盐酸盐
- NΑ-甲苯磺胺基-L-赖氨酸氯甲基酮盐酸盐
- (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
- NA-对甲苯磺酰-L-赖氨酸氯甲基酮盐酸盐
- TLCK(进分)
- 4272-74-6
- N-[5-amino-1-(2-chloroacetyl)pentyl]-4-methyl-benzenesulfonamide, monohydrochloride
- Inhibitor,inhibit,N alpha Tosyl L lysine chloromethyl ketone hydrochloride,NalphaTosylLlysine chloromethyl ketone hydrochloride
- N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE (TLCK)
- N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE
- Nα-Tosyl-L-lysine chloromethyl ketone
- (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone HCl
- TLCK USP/EP/BP
- N-alpha-Tosyl-L-lysine chloromethyl ketone HCl
- Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride
- N-ALPHA-TOSYL-LYS-CHLOROMETHYLKETONE HCL
- N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
- N-ALPHA-TOSYL-L-LYS CHLOROMETHYLKETONE
- TLCK HYDROCHLORIDE
- TLCK HCL
- TLCK
- n-(5-amino-1-(chloroacetyl)pentyl)-,hydrochloride,l-p-toluenesulfonamid
- l-n-(5-amino-1-(chloroacetyl)pentyl)-p-toluenesulfonamidehydrochloride
- (s)-lorid
- Nα-Tosyl-L-lysine chloroMethyl ketone HCl
- (3S)-1-Chloro-3-tosylaMido-7-aMino-2-heptanone hydrochloride, 98% 50MG
- Tos-Lys-chloromethylketone
- (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride,98%
- NALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE (TLCK)
- Benzenesulfonamide, N-(1S)-5-amino-1-(chloroacetyl)pentyl-4-methyl-, monohydrochloride
- (S)-N-[5-amino-1-(chloroacetyl)pentyl]-p-toluenesulphonamide monohydrochloride
- n-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-benzenesulfonamidmonohydroch
- Chloro-3-tosylaMido-7-aMino-2-heptanone-HCl research grade
- 1-CHLORO-3-TOSYLAMIDO-7-AMINO-L-2-HEPTANONE HYDROCHLORIDE