(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
|
|
|
- CAS号:
- 4272-74-6
- 英文名:
- TLCK
- 英文别名:
- TLCK;TLCK HCL;(s)-lorid;TOS-LYS-CMK;TOSYL-LYS-CMK;TLCK USP/EP/BP;TOS-LYS-CMK HCL;Tos-L-Lys-CMK·HCl;TLCK HYDROCHLORIDE;Tos-Lys-chloromethylketone
- 中文名:
- (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
- 中文别名:
- TLCK(进分);化合物 T16169;NA-对甲苯磺酰-L-赖氨酸氯甲基酮盐酸盐;NΑ-甲苯磺胺基-L-赖氨酸氯甲基酮盐酸盐;NΑ-甲苯磺酰基-L-赖氨酸氯甲基酮盐酸盐;NALPHA-甲苯磺胺基-L-赖氨酸氯甲基酮盐酸盐;(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐;(3S)-1-氯-3-甲苯磺酰基氨-7-氨基-2-庚酮盐酸盐;NΑ-甲苯磺酰基- L -赖氨酸氯甲基酮 盐酸盐;化合物N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
- CBNumber:
- CB1197729
- 分子式:
- C14H22Cl2N2O3S
- 分子量:
- 369.31
- MOL File:
- 4272-74-6.mol
|
|
|
(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐化学性质
-
熔点:
-
~165 °C (dec.)
-
|
-
储存条件:
-
-20°C
-
|
-
溶解度:
-
H2O: 50 mg/mL
-
|
-
形态:
-
powder
-
|
-
颜色:
-
white to pink
-
|
-
旋光性 (optical activity):
-
[α]20/D 7.8±0.5°, c = 2% in H2O
-
|
-
BRN:
-
7106867
-
|
-
CAS 数据库:
-
4272-74-6
-
|
(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐性质、用途与生产工艺
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK) 是一种胰蛋白酶样蛋白酶抑制剂，使 HeLa 细胞对 Fas 介导的细胞死亡敏感。
N-alpha-Tosyl-L-lysine chloromethyl ketone exhibits an inhibitory effect on IFN-γ activities. The effect of TLCK is studied on the IFN-γ sensitization of HeLa cells towards cell death mediated by anti-Fas. Lower concentration of anti-Fas (10 ng/mL) are used to examine the interaction among the three effectors simultaneously, that is, anti-Fas, TLCK and IFN-γ. TLCK by itself up to 50 μM concentration exhibits a small decrease in cell viability. Beyond 50 μM, a dose dependent decrease in cell viability is observed. IFN-γ slightly reduces cell viability on its own. Addition of anti-Fas (10 ng/mL) results in a slight decrease in cell survival, which is enhanced more than additively in the presence of TLCK, most prominently between 50 and 100 μM. Upon addition of both anti-Fas and IFN-γ, a decrease (≈46%) in cell viability is observed. Moreover, the decrease in cell survival is further enhanced upon addition of higher concentrations of TLCK, 25 μM and more.
(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | C22795 | (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
(3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, 98% | 4272-74-6 | 50mg | 804元 |
| 2024/04/30 | C22795 | (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
(3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, 98% | 4272-74-6 | 250mg | 3257元 |
(3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
生产厂家
4272-74-6, (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐 相关搜索:
- inhibitor
- 高端化学
- 通用生化试剂-氨基酸
- 生化试剂-氨基酸类
- 蛋白酶抑制剂
- 氨基酸类
- 氨基酸
- 细胞裂解蛋白酶抑制剂
- Trypsin Inhibitors
- Enzyme Inhibitors by Type
- Enzymes, Inhibitors, and Substrates
- Enzyme Inhibitors
- Analytical Enzymes
- Biochemicals and Reagents
- BioChemical
- Organic Covalent Modifiers
- C14H22N2O3Scl
- C14H21ClN2O3S
- C14H21ClN2O3SHCl
- NΑ-甲苯磺酰基- L -赖氨酸氯甲基酮 盐酸盐
- 化合物N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
- 化合物 T16169
- NΑ-甲苯磺酰基-L-赖氨酸氯甲基酮盐酸盐
- NALPHA-甲苯磺胺基-L-赖氨酸氯甲基酮盐酸盐
- (3S)-1-氯-3-甲苯磺酰基氨-7-氨基-2-庚酮盐酸盐
- NΑ-甲苯磺胺基-L-赖氨酸氯甲基酮盐酸盐
- (3S)-7-氨基-1-氯-3-磺酰氨基-2-庚酮盐酸盐
- NA-对甲苯磺酰-L-赖氨酸氯甲基酮盐酸盐
- TLCK(进分)
- 4272-74-6
- Inhibitor,inhibit,N alpha Tosyl L lysine chloromethyl ketone hydrochloride,NalphaTosylLlysine chloromethyl ketone hydrochloride
- N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE (TLCK)
- N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE
- Nα-Tosyl-L-lysine chloromethyl ketone
- (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone HCl
- TLCK USP/EP/BP
- N-alpha-Tosyl-L-lysine chloromethyl ketone HCl
- Nα-Tosyl-L-lysine chloromethyl ketone hydrochloride
- N-ALPHA-TOSYL-LYS-CHLOROMETHYLKETONE HCL
- N-ALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE
- N-ALPHA-TOSYL-L-LYS CHLOROMETHYLKETONE
- TLCK HYDROCHLORIDE
- TLCK HCL
- TLCK
- n-(5-amino-1-(chloroacetyl)pentyl)-,hydrochloride,l-p-toluenesulfonamid
- l-n-(5-amino-1-(chloroacetyl)pentyl)-p-toluenesulfonamidehydrochloride
- (s)-lorid
- Nα-Tosyl-L-lysine chloroMethyl ketone HCl
- (3S)-1-Chloro-3-tosylaMido-7-aMino-2-heptanone hydrochloride, 98% 50MG
- Tos-Lys-chloromethylketone
- (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride,98%
- NALPHA-TOSYL-L-LYSINE CHLOROMETHYL KETONE HYDROCHLORIDE (TLCK)
- Benzenesulfonamide, N-(1S)-5-amino-1-(chloroacetyl)pentyl-4-methyl-, monohydrochloride
- (S)-N-[5-amino-1-(chloroacetyl)pentyl]-p-toluenesulphonamide monohydrochloride
- n-(5-amino-1-(chloroacetyl)pentyl)-4-methyl-benzenesulfonamidmonohydroch
- Chloro-3-tosylaMido-7-aMino-2-heptanone-HCl research grade
- 1-CHLORO-3-TOSYLAMIDO-7-AMINO-L-2-HEPTANONE HYDROCHLORIDE
- 1-CHLORO-3-TOSYLAMIDO-7-AMINO-L-2-HEPTANONE